This preprint is under consideration at BMC Cardiovascular Disorders. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Research article
Health-related Quality of Life in Men and Women who Experienced Cardiovascular Diseases: Tehran Lipid and Glucose Study
Parisa Amiri
Research Institute for Endocrine Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3198-4941
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Cardiovascular diseases (CVDs) are among the most common causes of death worldwide, including in Iran. Considering the adverse effects of CVDs on physical and psychosocial health; this study aims to investigate the association between CVDs incidence and health-related quality of life (HRQoL) in adult participants of the Tehran Lipid and Glucose Study (TLGS).
Methods: The participants of this cross-sectional study were 7009 adults (≥20 years) who participated in the TLGS during 2014-2017. Demographic information and HRQoL data was collected through validated questionnaires by trained interviewers. HRQoL was assessed by the Iranian version of the SF-12 questionnaire. Data was analyzed using SPSS software.
Results: The mean age of participants was 46.8±14.6 years and 46.1% of them were men. A total of 9.0% of men and 4.4% of women had CVDs. In men, the mean physical HRQoL summary score was significantly lower in those with CVDs compared to those without CVDs (46.6±0.8 vs. 48.5±0.7, p >0.001). In women, the mean mental HRQoL summary scores was significantly lower in those with CVDs compared to those without CVDs (42.8±1.0 vs. 45.2±0.5, p =0.009). In adjusted models, men with CVDs were more likely to report poor physical HRQoL compared to men without CVDs (OR(95%CI): 1.93(1.32-2.84), p=0.001); whereas for women, the chance of reporting poor mental HRQoL was 68% higher in those with CVDs than those without CVDs (OR(95%CI): 1.68(1.11-2.54), p =0.015).
Conclusion: The findings of the current study indicate poorer HRQoL in those who experienced CVDs compared to their healthy counterparts with a sex specific pattern. While for men, CVDs were associated with greater impairment in the physical dimension of HRQoL, women experienced a similar impairment in the mental dimension of HRQoL.
Keywords
Cardiovascular diseases, health-related quality of life, adults, Tehran Lipid and Glucose Study
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CURRENT STATUS: Under Review
Version 1
Posted 24 Sep, 2020
No community comments so far
Reviewer #2 agreed
On 19 Nov, 2020
Reviewer #1 agreed
On 27 Oct, 2020
Reviewers invited
Invitations sent on 30 Sep, 2020
Editor assigned
On 17 Sep, 2020
Submission checks complete
On 16 Sep, 2020
Editor invited
On 16 Sep, 2020
First submitted
On 15 Sep, 2020
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Subject Areas
Cardiac & Cardiovascular Systems
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This preprint is under consideration at BMC Cardiovascular Disorders. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Health-related Quality of Life in Men and Women who Experienced Cardiovascular Diseases: Tehran Lipid and Glucose Study
Parisa Amiri
Research Institute for Endocrine Sciences
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3198-4941
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 24 Sep, 2020
No community comments so far
Reviewer #2 agreed
On 19 Nov, 2020
Reviewer #1 agreed
On 27 Oct, 2020
Reviewers invited
Invitations sent on 30 Sep, 2020
Editor assigned
On 17 Sep, 2020
Submission checks complete
On 16 Sep, 2020
Editor invited
On 16 Sep, 2020
First submitted
On 15 Sep, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Cardiac & Cardiovascular Systems
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Cardiovascular diseases (CVDs) are among the most common causes of death worldwide, including in Iran. Considering the adverse effects of CVDs on physical and psychosocial health; this study aims to investigate the association between CVDs incidence and health-related quality of life (HRQoL) in adult participants of the Tehran Lipid and Glucose Study (TLGS).
Methods: The participants of this cross-sectional study were 7009 adults (≥20 years) who participated in the TLGS during 2014-2017. Demographic information and HRQoL data was collected through validated questionnaires by trained interviewers. HRQoL was assessed by the Iranian version of the SF-12 questionnaire. Data was analyzed using SPSS software.
Results: The mean age of participants was 46.8±14.6 years and 46.1% of them were men. A total of 9.0% of men and 4.4% of women had CVDs. In men, the mean physical HRQoL summary score was significantly lower in those with CVDs compared to those without CVDs (46.6±0.8 vs. 48.5±0.7, p >0.001). In women, the mean mental HRQoL summary scores was significantly lower in those with CVDs compared to those without CVDs (42.8±1.0 vs. 45.2±0.5, p =0.009). In adjusted models, men with CVDs were more likely to report poor physical HRQoL compared to men without CVDs (OR(95%CI): 1.93(1.32-2.84), p=0.001); whereas for women, the chance of reporting poor mental HRQoL was 68% higher in those with CVDs than those without CVDs (OR(95%CI): 1.68(1.11-2.54), p =0.015).
Conclusion: The findings of the current study indicate poorer HRQoL in those who experienced CVDs compared to their healthy counterparts with a sex specific pattern. While for men, CVDs were associated with greater impairment in the physical dimension of HRQoL, women experienced a similar impairment in the mental dimension of HRQoL.