A 14-year-old previously healthy girl was admitted to our Pediatric Surgical Department for 10-days history of fever (>38.5 °C) associated with abdominal pain, vomiting and diarrhea. A blood test showed a neutrophilic leukocytosis with elevated levels of C-Reactive Protein (WBC 25000 mm3, Neutrophils 80%, CRP 206 mg/L). Physical examination revealed a soft, nondistended abdomen with localized lower quadrants tenderness. An abdominal ultrasonography (US) documented a cavity distended by superfluid material and diffuse adipose-tissue hyperplasia. This cavity persisted also after defecation. Cecal appendix could not be well-recognized at imaging. A magnetic resonance imaging (MRI) confirmed the presence of a huge pelvic collection in the hypogastrium (12x10x11 cm) with air-fluid levels [Fig 1]
Occult intra-abdominal source of infection in patients with prolonged fever, elevated WBC and CRP must always be suspected [1]. In particular, complicated appendicitis should always be taken into consideration in case of prolonged fever and persistent abdominal pain [2]. Diagnosis of appendicitis is usually based on clinical examination, but it can often be supported by abdominal US [3,4]. Notably, in complex cases, MRI may be useful to depict relevant findings for alternative diagnoses [5,6].
The patient underwent a median laparotomy, and a purulent-fecal fluid (about 400 ml) was drained from a well-organized pelvic collection secondary to a perforated appendicitis. Appendectomy was then performed. The drain output decreased about 5ml per day and, consequently, the drainage was removed 4 days after surgery. Empiric intravenous antibiotics were administered for 10 days, and the patient was discharged home on post-operative day 12 in good health status.