Universal interaction reference systems in nature can’t avoid elastic inversion(memory). Newton established the parameter quantity-driving rigid reference system with zero inversion. Bio-systems fall to another extremity that can only utilize inversion energy without rigidness. We define inversion energy as parameter-against-gravity- internal-fluctuation for this system, write down modifications of Newtonian Three Laws as, first law: (𝑑/𝑑𝑥)cosx =−𝑠𝑖𝑛𝑥, (𝑑/𝑑𝑥)sinx = 𝑐𝑜𝑠𝑥; second law: 𝐹⃗=𝑚∙𝑎⃗ + |𝑚𝑔⃗∫𝑡𝑔𝜃⋅𝑑𝜃 ⟩↿⇂; third law: Wavelength = (2/𝑛)L, frequency = n𝑓0 . The Schrödinger equation has only quantized energy but still hasn’t quantized time thus inducing quantum collapse. We then conjugate inversion energy with quantizing time which composes of event inversion superposition to establish entropy-control lifespan for bio-systems. Originating from the gravitational folding of surface tension regions, bio quantum path duality fluctuation scales as macrocosmic elastic quantum ranges from a codon to the spinal size drives life folding or evolution. The biological functions including consciousness revive from the bio quantum path duality that modulates by the three modified laws.