Over the years, researchers have continuously searched for ways to achieve adsorption of heavy metal ions from the industrial effluents at lowest possible cost, which has resulted into the development of innumerous special type of low cost adsorbents, called biosorbents. While potential of many biosorbents have been explored in laboratory setup, very few studies have tried to scale up the biosorption process and predict the performance of these biosorbents in a large scale industrial setup. In this work, performance of laboratory synthesized dolochar has been investigated for adsorption of Cd2+ ions in a large scale process with the application of Aspen Adsorption. Moreover, the optimum values of the operating parameters (namely, flow rate, bed height and inlet metal ion concentration) that would result into maximum amount of cadmium ion adsorption (high exhaustion capacity) in minimum time (less exhaustion time) for a fixed mass of dolochar (1200 kg) have been calculated via the application of Response Surface Methodology. It was found out that, at optimum values of bed height (3.48 m), flow rate (76.31 m3/day) and inlet concentration (10 ppm), the optimized value of exhaustion capacity and exhaustion time for cadmium ion adsorption in dolochar packed bed is equal to 1.85 mg/g and 11.39 hours, respectively. The validity of these simulation experiments can be proven by the fact that the obtained exhaustion capacity of dolochar packed beds always remained in close proximity of the experimentally obtained value of adsorption capacity of the dolochar in batch process mode (equal to 2.1 mg/g).