1 DePalma, R. G., Burris, D. G., Champion, H. R. & Hodgson, M. J. Blast injuries. N Engl J Med 352, 1335-1342, doi:352/13/1335 [pii] 10.1056/NEJMra042083 (2005).
2 Cernak, I. & Noble-Haeusslein, L. J. Traumatic brain injury: an overview of pathobiology with emphasis on military populations. J Cereb Blood Flow Metab 30, 255-266, doi:jcbfm2009203 [pii] 10.1038/jcbfm.2009.203 (2010).
3 Rosenfeld, J. V. et al. Blast-related traumatic brain injury. Lancet Neurol 12, 882-893, doi:S1474-4422(13)70161-3 [pii] 10.1016/S1474-4422(13)70161-3 (2013).
4 Wolf, S. J., Bebarta, V. S., Bonnett, C. J., Pons, P. T. & Cantrill, S. V. Blast injuries. Lancet 374, 405-415, doi:S0140-6736(09)60257-9 [pii] 10.1016/S0140-6736(09)60257-9 (2009).
5 Hoge, C. W. et al. Mild traumatic brain injury in U.S. Soldiers returning from Iraq. N Engl J Med 358, 453-463, doi:NEJMoa072972 [pii]10.1056/NEJMoa072972 (2008).
6 Sosa, M. A. et al. Blast overpressure induces shear-related injuries in the brain of rats exposed to a mild traumatic brain injury. Acta Neuropathol Commun 1, 51, doi:10.1186/2051-5960-1-51 (2013).
7 Svetlov, S. I. et al. Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to "composite" blast. Front Neurol 3, 15, doi:10.3389/fneur.2012.00015 (2012).
8 Mishra, V. et al. Primary blast causes mild, moderate, severe and lethal TBI with increasing blast overpressures: Experimental rat injury model. Scientific reports 6, 26992, doi:10.1038/srep26992 (2016).
9 Courtney, A. & Courtney, M. The Complexity of Biomechanics Causing Primary Blast-Induced Traumatic Brain Injury: A Review of Potential Mechanisms. Front Neurol 6, 221, doi:10.3389/fneur.2015.00221 (2015).
10 Cernak, I. Understanding blast-induced neurotrauma: how far have we come? Concussion 2, CNC42, doi:10.2217/cnc-2017-0006 (2017).
11 Masel, B. E. et al. Galveston Brain Injury Conference 2010: clinical and experimental aspects of blast injury. J Neurotrauma 29, 2143-2171, doi:10.1089/neu.2011.2258 (2012).
12 Davidsson, J., Angeria, M. & Risling, M. in International IRCOBI conference on the biomechanics of injury.
13 Rowson, S. et al. Rotational head kinematics in football impacts: an injury risk function for concussion. Ann Biomed Eng 40, 1-13, doi:10.1007/s10439-011-0392-4 (2012).
14 Smith, D. H. et al. Pre-Clinical Traumatic Brain Injury Common Data Elements: Toward a Common Language Across Laboratories. J Neurotrauma 32, 1725-1735, doi:10.1089/neu.2014.3861 (2015).
15 Percie du Sert, N. et al. The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. J Physiol, doi:10.1113/JP280389 (2020).
16 Chen, Y. & Huang, W. Non-impact, blast-induced mild TBI and PTSD: concepts and caveats. Brain Inj 25, 641-650, doi:10.3109/02699052.2011.580313 (2011).
17 Nadler, J. V. & Evenson, D. A. Use of excitatory amino acids to make axon-sparing lesions of hypothalamus. Methods Enzymol 103, 393-400 (1983).
18 Gallyas, F., Wolff, J. R., Bottcher, H. & Zaborszky, L. A reliable method for demonstrating axonal degeneration shortly after axotomy. Stain Technol 55, 291-297, doi:10.3109/10520298009067257 (1980).
19 Schmued, Lc, Hopkins & Kj. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res 874, 123-130 (2000).
20 Won, S. J. et al. EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia. J Neurosci 30, 15409-15418, doi:10.1523/JNEUROSCI.2084-10.2010 (2010).
21 Shridharani, J. K. et al. Porcine head response to blast. Front Neurol 3, 70, doi:10.3389/fneur.2012.00070 (2012).
22 Gullotti, D. M. et al. Significant head accelerations can influence immediate neurological impairments in a murine model of blast-induced traumatic brain injury. J Biomech Eng 136, 091004, doi:10.1115/1.4027873 (2014).
23 Irvine, K. et al. Effects of veliparib on microglial activation and functional outcomes following traumatic brain injury in the rat and pig. J Neurotrauma, doi:10.1089/neu.2017.5044 (2017).
24 Kashalikar, S. J. An explanation for the development of decussations in the central nervous system. Med Hypotheses 26, 1-8, doi:0306-9877(88)90103-X [pii] (1988).
25 Xiao-Sheng, H., Sheng-Yu, Y., Xiang, Z., Zhou, F. & Jian-ning, Z. Diffuse axonal injury due to lateral head rotation in a rat model. J Neurosurg 93, 626-633, doi:10.3171/jns.2000.93.4.0626 (2000).
26 Frank, D. et al. Induction of Diffuse Axonal Brain Injury in Rats Based on Rotational Acceleration. J Vis Exp, doi:10.3791/61198 (2020).
27 Sauerbeck, A. D. et al. modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury. Scientific reports 8, 7677, doi:10.1038/s41598-018-25737-6 (2018).
28 Davidsson, J. & Risling, M. A new model to produce sagittal plane rotational induced diffuse axonal injuries. Front Neurol 2, 41, doi:10.3389/fneur.2011.00041 (2011).
29 Tang-Schomer, M. D., Johnson, V. E., Baas, P. W., Stewart, W. & Smith, D. H. Partial interruption of axonal transport due to microtubule breakage accounts for the formation of periodic varicosities after traumatic axonal injury. Exp Neurol 233, 364-372, doi:10.1016/j.expneurol.2011.10.030 (2012).
30 Johnson, V. E., Stewart, W. & Smith, D. H. Axonal pathology in traumatic brain injury. Exp Neurol 246, 35-43, doi:10.1016/j.expneurol.2012.01.013 (2013).
31 Vazquez-Rosa, E. et al. P7C3-A20 treatment one year after TBI in mice repairs the blood-brain barrier, arrests chronic neurodegeneration, and restores cognition. Proc Natl Acad Sci U S A 117, 27667-27675, doi:10.1073/pnas.2010430117 (2020).
32 Faden, A. I., Wu, J., Stoica, B. A. & Loane, D. J. Progressive inflammation-mediated neurodegeneration after traumatic brain or spinal cord injury. Br J Pharmacol 173, 681-691, doi:10.1111/bph.13179 (2016).
33 Switzer, R. C., 3rd. Application of silver degeneration stains for neurotoxicity testing. Toxicol Pathol 28, 70-83, doi:10.1177/019262330002800109 (2000).
34 Beltramino, C. A., de Olmos, J. S., Gallyas, F., Heimer, L. & Zaborszky, L. Silver staining as a tool for neurotoxic assessment. NIDA Res Monogr 136, 101-126; discussion 126-132, doi:10.1037/e495922006-007 (1993).
35 Bennett, R. E., Mac Donald, C. L. & Brody, D. L. Diffusion tensor imaging detects axonal injury in a mouse model of repetitive closed-skull traumatic brain injury. Neurosci Lett 513, 160-165, doi:10.1016/j.neulet.2012.02.024 (2012).
36 Shitaka, Y. et al. Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivity. J Neuropathol Exp Neurol 70, 551-567, doi:10.1097/NEN.0b013e31821f891f (2011).
37 Garman, R. H. et al. Blast exposure in rats with body shielding is characterized primarily by diffuse axonal injury. J Neurotrauma 28, 947-959, doi:10.1089/neu.2010.1540 (2011).
38 Tompkins, P. et al. Brain injury: neuro-inflammation, cognitive deficit, and magnetic resonance imaging in a model of blast induced traumatic brain injury. J Neurotrauma 30, 1888-1897, doi:10.1089/neu.2012.2674 (2013).
39 Yeoh, S., Bell, E. D. & Monson, K. L. Distribution of blood-brain barrier disruption in primary blast injury. Ann Biomed Eng 41, 2206-2214, doi:10.1007/s10439-013-0805-7 (2013).
40 Kuehn, R. et al. Rodent model of direct cranial blast injury. J Neurotrauma 28, 2155-2169, doi:10.1089/neu.2010.1532 (2011).
41 Kawa, L. et al. A Comparative Study of Two Blast-Induced Traumatic Brain Injury Models: Changes in Monoamine and Galanin Systems Following Single and Repeated Exposure. Front Neurol 9, 479, doi:10.3389/fneur.2018.00479 (2018).
42 Svetlov, S. I. et al. Morphologic and biochemical characterization of brain injury in a model of controlled blast overpressure exposure. J Trauma 69, 795-804, doi:10.1097/TA.0b013e3181bbd885 (2010).
43 Readnower, R. D. et al. Increase in blood-brain barrier permeability, oxidative stress, and activated microglia in a rat model of blast-induced traumatic brain injury. J Neurosci Res 88, 3530-3539, doi:10.1002/jnr.22510 (2010).
44 Ordek, G. et al. Electrophysiological Correlates of Blast-Wave Induced Cerebellar Injury. Scientific reports 8, 13633, doi:10.1038/s41598-018-31728-4 (2018).
45 Logsdon, A. F. et al. Nitric oxide synthase mediates cerebellar dysfunction in mice exposed to repetitive blast-induced mild traumatic brain injury. Scientific reports 10, 9420, doi:10.1038/s41598-020-66113-7 (2020).
46 Koliatsos, V. E. et al. A mouse model of blast injury to brain: initial pathological, neuropathological, and behavioral characterization. J Neuropathol Exp Neurol 70, 399-416, doi:10.1097/NEN.0b013e3182189f06 (2011).
47 Calabrese, E. et al. Diffusion tensor imaging reveals white matter injury in a rat model of repetitive blast-induced traumatic brain injury. J Neurotrauma 31, 938-950, doi:10.1089/neu.2013.3144 (2014).
48 Peskind, E. R. et al. Cerebrocerebellar hypometabolism associated with repetitive blast exposure mild traumatic brain injury in 12 Iraq war Veterans with persistent post-concussive symptoms. Neuroimage 54 Suppl 1, S76-82, doi:S1053-8119(10)00402-7 [pii]10.1016/j.neuroimage.2010.04.008 (2011).
49 Mac Donald, C. L. et al. Detection of blast-related traumatic brain injury in U.S. military personnel. N Engl J Med 364, 2091-2100, doi:10.1056/NEJMoa1008069 (2011).
50 Meabon, J. S. et al. Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Sci Transl Med 8, 321ra326, doi:8/321/321ra6 [pii]10.1126/scitranslmed.aaa9585 (2016).
51 Rabellino, D., Densmore, M., Theberge, J., McKinnon, M. C. & Lanius, R. A. The cerebellum after trauma: Resting-state functional connectivity of the cerebellum in posttraumatic stress disorder and its dissociative subtype. Hum Brain Mapp 39, 3354-3374, doi:10.1002/hbm.24081 (2018).
52 Petras, J. M., Bauman, R. A. & Elsayed, N. M. Visual system degeneration induced by blast overpressure. Toxicology 121, 41-49, doi:S0300483X97036548 [pii] (1997).
53 DeMar, J. et al. Effects of Primary Blast Overpressure on Retina and Optic Tract in Rats. Front Neurol 7, 59, doi:10.3389/fneur.2016.00059 (2016).
54 Bricker-Anthony, C., Hines-Beard, J. & Rex, T. S. Molecular changes and vision loss in a mouse model of closed-globe blast trauma. Invest Ophthalmol Vis Sci 55, 4853-4862, doi:iovs.14-14353 [pii]10.1167/iovs.14-14353 (2014).
55 Jean, A. et al. An animal-to-human scaling law for blast-induced traumatic brain injury risk assessment. Proc Natl Acad Sci U S A 111, 15310-15315, doi:1415743111 [pii]10.1073/pnas.1415743111 (2014).
56 Chandra, N., Sundaramurthy, A. & Gupta, R. K. Validation of Laboratory Animal and Surrogate Human Models in Primary Blast Injury Studies. Mil Med 182, 105-113, doi:10.7205/MILMED-D-16-00144 (2017).
57 Needham, C. E., Ritzel, D., Rule, G. T., Wiri, S. & Young, L. Blast Testing Issues and TBI: Experimental Models That Lead to Wrong Conclusions. Front Neurol 6, 72, doi:10.3389/fneur.2015.00072 (2015).
58 Turner, R. C. et al. Modeling clinically relevant blast parameters based on scaling principles produces functional & histological deficits in rats. Exp Neurol 248, 520-529, doi:10.1016/j.expneurol.2013.07.008 (2013).
59 Cernak, I. Blast-induced neurotrauma models and their requirements. Front Neurol 5, 128, doi:10.3389/fneur.2014.00128 (2014).
60 Kumar, R. & Nedungadi, A. Using Gas-Driven Shock Tubes to Produce Blast Wave Signatures. Front Neurol 11, 90, doi:10.3389/fneur.2020.00090 (2020).
61 Bowen, I. G., Fletcher, E. R., Richmond, D. R., Hirsch, F. G. & White, C. S. Biophysical mechanisms and scaling procedures applicable in assessing responses of the thorax energized by air-blast overpressures or by nonpenetrating missiles. Ann N Y Acad Sci 152, 122-146, doi:10.1111/j.1749-6632.1968.tb11971.x (1968).