Entrepreneurial intention has been found to be fundamental to decision-making and behavior to become entrepreneurs, with consequent effects on economic development. However, the COVID-19 pandemic calls for a novel approach to teaching entrepreneurship owing to the shift to online learning. The current study explores entrepreneurial intention derived from the entrepreneurship education program (EEP) using an online group-based learning approach. In particular, we examine satisfaction with an online group-based learning approach by integrating the theory of planned behavior with design thinking-based entrepreneurship course, peer interactions, and speaker interactions. The entrepreneurship education program (EEP) in this research was for vocational college students located in Southeast Asia. The online questionnaire was distributed to participants (N = 263, MAGE = 18.64) at the end of the online entrepreneurship education program. The model was tested using a structural equation model analysis. Attitude, subject norm, and satisfaction were found to predict higher entrepreneurial intention among vocational college students. Moreover, design thinking-based entrepreneurship course, peer interaction, and speaker interaction have indirect effects on entrepreneurial intention through satisfaction. This research extends the literature on entrepreneurship education by proposing a novel learning approach, that is, the online groupbased learning approach, which could be applied to entrepreneurship education programs to enhance students’ entrepreneurial intention.