1. Global Initiative for Asthma. Global Initiative for Asthma. Strategy for Asthma Management and Prevention, 2020. Available from Www.Ginasthma.Org.; 2020. www.ginasthma.org. Accessed October 15, 2020.
2. Wenzel SE. Asthma phenotypes: The evolution from clinical to molecular approaches. Nat Med. 2012;18(5):716-725. doi:10.1038/nm.2678
3. Cockcroft DW. Allergen-Induced Asthma. Vol 21. Hindawi Limited; 2014.
4. Diamant Z, Gauvreau GM, Cockcroft DW, et al. Inhaled allergen bronchoprovocation tests. J Allergy Clin Immunol. 2013;132(5). doi:10.1016/j.jaci.2013.08.023
5. Murdoch JR, Lloyd CM. Chronic inflammation and asthma. Mutat Res - Fundam Mol Mech Mutagen. 2010;690(1-2):24-39. doi:10.1016/j.mrfmmm.2009.09.005
6. Stenberg H, Diamant Z, Ankerst J, Bjermer L, Tufvesson E. Small airway involvement in the late allergic response in asthma. Clin Exp Allergy. 2017;47(12):1555-1565. doi:10.1111/cea.13036
7. Bergeron C, Tulic MK, Hamid Q. Airway remodelling in asthma: From benchside to clinical practice. Can Respir J. 2010;17(4). doi:10.1155/2010/318029
8. Nihlberg K, Larsen K, Hultgårdh-Nilsson A, Malmström A, Bjermer L, Westergren-Thorsson G. Tissue fibrocytes in patients with mild asthma: A possible link to thickness of reticular basement membrane? Respir Res. 2006;7(1). doi:10.1186/1465-9921-7-50
9. Fischer KD, Agrawal DK. Hematopoietic stem and progenitor cells in inflammation and allergy. Front Immunol. 2013;4(DEC). doi:10.3389/fimmu.2013.00428
10. Tacke F, Randolph GJ. Migratory fate and differentiation of blood monocyte subsets. Immunobiology. 2006;211(6-8):609-618. doi:10.1016/j.imbio.2006.05.025
11. Sbaa-Ketata E, Courel M-N, Delpech B, Vannier J-P. Hyaluronan‐Derived Oligosaccharides Enhance SDF‐1‐Dependent Chemotactic Effect on Peripheral Blood Hematopoietic CD34+ Cells. Stem Cells. 2002;20(6):585-587. doi:10.1634/stemcells.20-6-585
12. Suess PM, Chinea LE, Pilling D, Gomer RH. Extracellular Polyphosphate Promotes Macrophage and Fibrocyte Differentiation, Inhibits Leukocyte Proliferation, and Acts as a Chemotactic Agent for Neutrophils. J Immunol. 2019;203(2):493-499. doi:10.4049/jimmunol.1801559
13. White MJ V., Galvis-Carvajal E, Gomer RH. A Brief Exposure to Tryptase or Thrombin Potentiates Fibrocyte Differentiation in the Presence of Serum or Serum Amyloid P. J Immunol. 2015;194(1):142-150. doi:10.4049/jimmunol.1401777
14. Graham BL, Steenbruggen I, Barjaktarevic IZ, et al. Standardization of spirometry 2019 update an official American Thoracic Society and European Respiratory Society technical statement. Am J Respir Crit Care Med. 2019;200(8):E70-E88. doi:10.1164/rccm.201908-1590ST
15. Stenberg H, Wadelius E, Moitra S, et al. Club cell protein (CC16) in plasma, bronchial brushes, BAL and urine following an inhaled allergen challenge in allergic asthmatics. Biomarkers. 2018;23(1):51-60. doi:10.1080/1354750X.2017.1375559
16. Perez-Riverol Y, Csordas A, Bai J, et al. The PRIDE database and related tools and resources in 2019: Improving support for quantification data. Nucleic Acids Res. 2019;47(D1):D442-D450. doi:10.1093/nar/gky1106
17. Zhu Y, Orre LM, Tran YZ, et al. DEqMS: A Method for Accurate Variance Estimation in Differential Protein Expression Analysis. Mol Cell Proteomics. 2020;19:1047-1057. doi:10.1074/mcp.TIR119.001646
18. Szklarczyk D, Franceschini A, Wyder S, et al. STRING v10: Protein-protein interaction networks, integrated over the tree of life. Nucleic Acids Res. 2015;43(D1):D447-D452. doi:10.1093/nar/gku1003
19. Ashburner M, Ball CA, Blake JA, et al. Gene ontology: Tool for the unification of biology. Nat Genet. 2000;25(1):25-29. doi:10.1038/75556
20. Carbon S, Douglass E, Good BM, et al. The Gene Ontology resource: Enriching a GOld mine. Nucleic Acids Res. 2021;49(D1):D325-D334. doi:10.1093/nar/gkaa1113
21. Bates D, Mächler M, Bolker BM, Walker SC. Fitting linear mixed-effects models using lme4. J Stat Softw. 2015;67(1):1-48. doi:10.18637/jss.v067.i01
22. Daniel Lüdecke. sjPlot: Data Visualization for Statistics in Social Science. 2020. https://cran.r-project.org/package=sjPlot.
23. Nakamura K, Igarashi K, Ide K, et al. Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. Clin Chim Acta. 2008;388(1-2):51-58. doi:10.1016/j.cca.2007.10.005
24. Park GY, Lee YG, Berdyshev E, et al. Autotaxin production of lysophosphatidic acid mediates allergic asthmatic inflammation. Am J Respir Crit Care Med. 2013;188(8):928-940. doi:10.1164/rccm.201306-1014OC
25. Wang H, E. Sama A. Anti-Inflammatory Role of Fetuin-A in Injury and Infection. Curr Mol Med. 2012;12(5):625-633. doi:10.2174/156652412800620039
26. Du Clos TW. Pentraxins: Structure, Function, and Role in Inflammation. ISRN Inflamm. 2013;2013:1-22. doi:10.1155/2013/379040
27. Wang S, Song R, Wang Z, Jing Z, Wang S, Ma J. S100A8/A9 in inflammation. Front Immunol. 2018;9(JUN):1298. doi:10.3389/fimmu.2018.01298
28. Sampath P, Moideen K, Ranganathan UD, Bethunaickan R. Monocyte Subsets: Phenotypes and Function in Tuberculosis Infection. Front Immunol. 2018;9:1726. doi:10.3389/fimmu.2018.01726
29. Zou YR, Kottman AH, Kuroda M, Taniuchi I, Littman DR. Function of the chemokine receptor CXCR4 in heaematopolesis and in cerebellar development. Nature. 1998;393(6685):595-599. doi:10.1038/31269
30. Mazo IB, Massberg S, von Andrian UH. Hematopoietic stem and progenitor cell trafficking. Trends Immunol. 2011;32(10):493-503. doi:10.1016/j.it.2011.06.011
31. Kariyawasam HH, Aizen M, Barkans J, Robinson DS, Kay AB. Remodeling and airway hyperresponsiveness but not cellular inflammation persist after allergen challenge in asthma. Am J Respir Crit Care Med. 2007;175(9):896-904. doi:10.1164/rccm.200609-1260OC
32. GM G, RM W, PM O. Kinetics of allergen-induced airway eosinophilic cytokine production and airway inflammation. Am J Respir Crit Care Med. 1999;160(2):640-647. doi:10.1164/AJRCCM.160.2.9809130
33. Zuiker RGJA, Ruddy MK, Morelli N, et al. Kinetics of TH2 biomarkers in sputum of asthmatics following inhaled allergen. Eur Clin Respir J. 2015;2(1):28319. doi:10.3402/ECRJ.V2.28319
34. Zuiker RGJA, Tribouley C, Diamant Z, et al. Sputum RNA signature in allergic asthmatics following allergen bronchoprovocation test. Eur Clin Respir J. 2016;3(1):31324. doi:10.3402/ECRJ.V3.31324
35. Jain S, Gautam V, Naseem S. Acute-phase proteins: As diagnostic tool. J Pharm Bioallied Sci. 2011;3(1):118-127. doi:10.4103/0975-7406.76489
36. Maharjan AS, Roife D, Brazill D, Gomer RH. Serum amyloid P inhibits granulocyte adhesion. Fibrogenes Tissue Repair. 2013;6(1):2. doi:10.1186/1755-1536-6-2
37. Pilling D, Galvis-Carvajal E, Karhadkar TR, Cox N, Gomer RH. Monocyte differentiation and macrophage priming are regulated differentially by pentraxins and their ligands. BMC Immunol. 2017;18(1). doi:10.1186/s12865-017-0214-z
38. Lu J, Marnell LL, Marjon KD, Mold C, Du Clos TW, Sun PD. Structural recognition and functional activation of FcγR by innate pentraxins. Nature. 2008;456(7224):989-992. doi:10.1038/nature07468
39. Castaño AP, Lin SL, Surowy T, et al. Serum amyloid P inhibits fibrosis through FcγR-dependent monocyte-macrophage regulation in vivo. Sci Transl Med. 2009;1(5):5ra13. doi:10.1126/scitranslmed.3000111
40. Perrakis A, Moolenaar WH. Thematic Review Series: Lysophospholipids and their Receptors: Autotaxin: Structure-function and signaling. J Lipid Res. 2014;55(6):1010-1018. doi:10.1194/jlr.R046391
41. Benesch MGK, Zhao YY, Curtis JM, McMullen TPW, Brindley DN. Regulation of autotaxin expression and secretion by lysophosphatidate and sphingosine 1-phosphate. J Lipid Res. 2015;56(6):1134-1144. doi:10.1194/jlr.M057661
42. O’Brien M. The Reciprocal Relationship Between Inflammation and Coagulation. Top Companion Anim Med. 2012;27(2):46-52. doi:10.1053/j.tcam.2012.06.003
43. Kowal K, Pampuch A, Kowal-Bielecka O, DuBuske LM, Bodzenta-Łukaszyk A. Platelet activation in allergic asthma patients during allergen challenge with Dermatophagoides pteronyssinus. Clin Exp Allergy. 2006;36(4):426-432. doi:10.1111/j.1365-2222.2006.02446.x
44. Petri B, Broermann A, Li H, et al. Von Willebrand factor promotes leukocyte extravasation. Blood. 2010;116(22):4712-4719. doi:10.1182/blood-2010-03-276311
45. Kawecki C, Lenting PJ, Denis C V. von Willebrand factor and inflammation. J Thromb Haemost. 2017;15(7):1285-1294. doi:10.1111/jth.13696
46. Muszbek L, Bereczky Z, Bagoly Z, Komáromi I, Katona É. Factor XIII: A coagulation factor with multiple plasmatic and cellular functions. Physiol Rev. 2011;91(3):931-972. doi:10.1152/physrev.00016.2010
47. Fukuda T, Mochida S, Fukushima Y, Makino S. Detection of allergen-induced genes in peripheral blood mononuclear cells of patients with allergic asthma using subtractive hybridization. J Allergy Clin Immunol. 1995;96(6 SUPPL.):1076-1082. doi:10.1016/S0091-6749(95)70193-1
48. Esnault S, Kelly EA, Sorkness RL, Evans MD, Busse WW, Jarjour NN. Airway factor XIII associates with type 2 inflammation and airway obstruction in asthmatic patients. J Allergy Clin Immunol. 2016;137(3):767-773.e6. doi:10.1016/j.jaci.2015.05.053
49. Lebreton JP, Joisel F, Raoult JP, Lannuzel B, Rogez JP, Humbert G. Serum concentration of human alpha2 HS glycoprotein during the inflammatory process. Evidence that alpha2 HS glycoprotein is a negative acute-phase reactant. J Clin Invest. 1979;64(4):1118-1129. doi:10.1172/JCI109551
50. Caillot N, Bouley J, Jain K, et al. Sialylated Fetuin-A as a candidate predictive biomarker for successful grass pollen allergen immunotherapy. J Allergy Clin Immunol. 2017;140(3):759-770.e13. doi:10.1016/j.jaci.2016.10.036
51. Schmidt M, Sun G, Stacey MA, Mori L, Mattoli S. Identification of Circulating Fibrocytes as Precursors of Bronchial Myofibroblasts in Asthma. J Immunol. 2003;171(1):380-389. doi:10.4049/jimmunol.171.1.380
52. Ji H, Liu XS. Analyzing ’omics Data Using Hierarchical Models. Vol 28. Nature Publishing Group; 2010:337-340. doi:10.1038/nbt.1619