[1]L. He, H. Li, A. Wu, Y. Peng, G. Shu, G. Yin, Functions of N6-methyladenosine and its role in cancer. Molecular cancer 18 (2019) 176.
[2]Y. Zhao, Y. Shi, H. Shen, W. Xie, m(6)A-binding proteins: the emerging crucial performers in epigenetics. Journal of hematology & oncology 13 (2020) 35.
[3]B. Tang, Y. Yang, M. Kang, Y. Wang, Y. Bi, S. He, F. Shimamoto, m(6)A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling. Molecular cancer 19 (2020) 3.
[4]S. Chen, C. Yang, Z.W. Wang, J.F. Hu, J.J. Pan, C.Y. Liao, J.Q. Zhang, J.Z. Chen, Y. Huang, L. Huang, Q. Zhan, Y.F. Tian, B.Y. Shen, Y.D. Wang, CLK1/SRSF5 pathway induces aberrant exon skipping of METTL14 and Cyclin L2 and promotes growth and metastasis of pancreatic cancer. Journal of hematology & oncology 14 (2021) 60.
[5]F. Tan, M. Zhao, F. Xiong, Y. Wang, S. Zhang, Z. Gong, X. Li, Y. He, L. Shi, F. Wang, B. Xiang, M. Zhou, Y. Li, G. Li, Z. Zeng, W. Xiong, C. Guo, N6-methyladenosine-dependent signalling in cancer progression and insights into cancer therapies. Journal of experimental & clinical cancer research : CR 40 (2021) 146.
[6]Y. Wu, N. Chang, Y. Zhang, X. Zhang, L. Xu, Y. Che, T. Qiao, B. Wu, Y. Zhou, J. Jiang, J. Xiong, J. Zhang, METTL3-mediated m(6)A mRNA modification of FBXW7 suppresses lung adenocarcinoma. Journal of experimental & clinical cancer research : CR 40 (2021) 90.
[7]B.S. Zhao, X. Wang, A.V. Beadell, Z. Lu, H. Shi, A. Kuuspalu, R.K. Ho, C. He, m(6)A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature 542 (2017) 475-478.
[8]K.J. Yoon, F.R. Ringeling, C. Vissers, F. Jacob, M. Pokrass, D. Jimenez-Cyrus, Y. Su, N.S. Kim, Y. Zhu, L. Zheng, S. Kim, X. Wang, L.C. Doré, P. Jin, S. Regot, X. Zhuang, S. Canzar, C. He, G.L. Ming, H. Song, Temporal Control of Mammalian Cortical Neurogenesis by m(6)A Methylation. Cell 171 (2017) 877-889 e817.
[9]D. Yang, J. Qiao, G. Wang, Y. Lan, G. Li, X. Guo, J. Xi, D. Ye, S. Zhu, W. Chen, W. Jia, Y. Leng, X. Wan, J. Kang, N6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential. Nucleic acids research 46 (2018) 3906-3920.
[10]J. Wen, R. Lv, H. Ma, H. Shen, C. He, J. Wang, F. Jiao, H. Liu, P. Yang, L. Tan, F. Lan, Y.G. Shi, Y. Shi, J. Diao, Zc3h13 Regulates Nuclear RNA m(6)A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Molecular cell 69 (2018) 1028-1038 e1026.
[11]T. Song, Y. Yang, H. Wei, X. Xie, J. Lu, Q. Zeng, J. Peng, Y. Zhou, S. Jiang, Zfp217 mediates m6A mRNA methylation to orchestrate transcriptional and post-transcriptional regulation to promote adipogenic differentiation. Nucleic acids research 47 (2019) 6130-6144.
[12]Q. Cui, H. Shi, P. Ye, L. Li, Q. Qu, G. Sun, Z. Lu, Y. Huang, C.G. Yang, A.D. Riggs, C. He, Y. Shi, m(6)A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell reports 18 (2017) 2622-2634.
[13]B.J. Hershey, R. Vazzana, D.L. Joppi, K.M. Havas, Lipid Droplets Define a Sub-Population of Breast Cancer Stem Cells. Journal of clinical medicine 9 (2019).
[14]J.A. Olzmann, P. Carvalho, Dynamics and functions of lipid droplets. Nature reviews. Molecular cell biology 20 (2019) 137-155.
[15]L. Tirinato, C. Liberale, S. Di Franco, P. Candeloro, A. Benfante, R. La Rocca, L. Potze, R. Marotta, R. Ruffilli, V.P. Rajamanickam, M. Malerba, F. De Angelis, A. Falqui, E. Carbone, M. Todaro, J.P. Medema, G. Stassi, E. Di Fabrizio, Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging. Stem Cells 33 (2015) 35-44.
[16]Y. Liu, S. Xu, C. Zhang, X. Zhu, M.A. Hammad, X. Zhang, M. Christian, H. Zhang, P. Liu, Hydroxysteroid dehydrogenase family proteins on lipid droplets through bacteria, C. elegans, and mammals. Biochimica et biophysica acta. Molecular and cell biology of lipids 1863 (2018) 881-894.
[17]Z. Zhang, J. Liu, C. Zhang, F. Li, L. Li, D. Wang, D. Chand, F. Guan, X. Zang, Y. Zhang, Over-Expression and Prognostic Significance of HHLA2, a New Immune Checkpoint Molecule, in Human Clear Cell Renal Cell Carcinoma. Frontiers in cell and developmental biology 8 (2020) 280.
[18]S. Li, D. Yue, X. Chen, L. Wang, J. Li, Y. Ping, Q. Gao, D. Wang, T. Zhang, F. Li, L. Yang, L. Huang, Y. Zhang, Epigenetic regulation of CD271, a potential cancer stem cell marker associated with chemoresistance and metastatic capacity. Oncology reports 33 (2015) 425-432.
[19]L. Li, L. Yang, Z. Fan, W. Xue, Z. Shen, Y. Yuan, X. Sun, D. Wang, J. Lian, L. Wang, J. Zhao, Y. Zhang, Hypoxia-induced GBE1 expression promotes tumor progression through metabolic reprogramming in lung adenocarcinoma. Signal transduction and targeted therapy 5 (2020) 54.
[20]H. Zhang, G. Qin, C. Zhang, H. Yang, J. Liu, H. Hu, P. Wu, S. Liu, L. Yang, X. Chen, X. Zhao, L. Wang, Y. Zhang, TRAIL promotes epithelial-to-mesenchymal transition by inducing PD-L1 expression in esophageal squamous cell carcinomas. Journal of experimental & clinical cancer research : CR 40 (2021) 209.
[21]S. Zhang, B.S. Zhao, A. Zhou, K. Lin, S. Zheng, Z. Lu, Y. Chen, E.P. Sulman, K. Xie, O. Bögler, S. Majumder, C. He, S. Huang, m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer cell 31 (2017) 591-606 e596.
[22]A. Deshmukh, K. Deshpande, F. Arfuso, P. Newsholme, A. Dharmarajan, Cancer stem cell metabolism: a potential target for cancer therapy. Molecular cancer 15 (2016) 69.
[23]S. Relier, J. Ripoll, H. Guillorit, A. Amalric, C. Achour, F. Boissiere, J. Vialaret, A. Attina, F. Debart, A. Choquet, F. Macari, V. Marchand, Y. Motorin, E. Samalin, J.J. Vasseur, J. Pannequin, F. Aguilo, E. Lopez-Crapez, C. Hirtz, E. Rivals, A. Bastide, A. David, FTO-mediated cytoplasmic m(6)Am demethylation adjusts stem-like properties in colorectal cancer cell. Nature communications 12 (2021) 1716.
[24]C. Mapperley, L.N. van de Lagemaat, H. Lawson, A. Tavosanis, J. Paris, J. Campos, D. Wotherspoon, J. Durko, A. Sarapuu, J. Choe, I. Ivanova, D.S. Krause, A. von Kriegsheim, C. Much, M. Morgan, R.I. Gregory, A.J. Mead, D. O'Carroll, K.R. Kranc, The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function. The Journal of experimental medicine 218 (2021).
[25]W. Xu, J. Li, C. He, J. Wen, H. Ma, B. Rong, J. Diao, L. Wang, J. Wang, F. Wu, L. Tan, Y.G. Shi, Y. Shi, H. Shen, METTL3 regulates heterochromatin in mouse embryonic stem cells. Nature 591 (2021) 317-321.
[26]G. Babaei, S.G. Aziz, N.Z.Z. Jaghi, EMT, cancer stem cells and autophagy; The three main axes of metastasis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 133 (2020) 110909.
[27]S. Zaccara, S.R. Jaffrey, A Unified Model for the Function of YTHDF Proteins in Regulating m(6)A-Modified mRNA. Cell 181 (2020) 1582-1595 e1518.
[28]X. Zhao, Y. Yang, B.F. Sun, Y. Shi, X. Yang, W. Xiao, Y.J. Hao, X.L. Ping, Y.S. Chen, W.J. Wang, K.X. Jin, X. Wang, C.M. Huang, Y. Fu, X.M. Ge, S.H. Song, H.S. Jeong, H. Yanagisawa, Y. Niu, G.F. Jia, W. Wu, W.M. Tong, A. Okamoto, C. He, J.M. Rendtlew Danielsen, X.J. Wang, Y.G. Yang, FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis. Cell research 24 (2014) 1403-1419.
[29]H. Kang, Z. Zhang, L. Yu, Y. Li, M. Liang, L. Zhou, FTO reduces mitochondria and promotes hepatic fat accumulation through RNA demethylation. Journal of cellular biochemistry 119 (2018) 5676-5685.
[30]T. Gerken, C.A. Girard, Y.C. Tung, C.J. Webby, V. Saudek, K.S. Hewitson, G.S. Yeo, M.A. McDonough, S. Cunliffe, L.A. McNeill, J. Galvanovskis, P. Rorsman, P. Robins, X. Prieur, A.P. Coll, M. Ma, Z. Jovanovic, I.S. Farooqi, B. Sedgwick, I. Barroso, T. Lindahl, C.P. Ponting, F.M. Ashcroft, S. O'Rahilly, C.J. Schofield, The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 318 (2007) 1469-1472.
[31]Y. Fu, G. Jia, X. Pang, R.N. Wang, X. Wang, C.J. Li, S. Smemo, Q. Dai, K.A. Bailey, M.A. Nobrega, K.L. Han, Q. Cui, C. He, FTO-mediated formation of N6-hydroxymethyladenosine and N6-formyladenosine in mammalian RNA. Nature communications 4 (2013) 1798.
[32]Z. Li, H. Weng, R. Su, X. Weng, Z. Zuo, C. Li, H. Huang, S. Nachtergaele, L. Dong, C. Hu, X. Qin, L. Tang, Y. Wang, G.M. Hong, X. Wang, P. Chen, S. Gurbuxani, S. Arnovitz, Y. Li, S. Li, J. Strong, M.B. Neilly, R.A. Larson, X. Jiang, P. Zhang, J. Jin, C. He, J. Chen, FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase. Cancer cell 31 (2017) 127-141.
[33]H. Huang, Y. Wang, M. Kandpal, G. Zhao, H. Cardenas, Y. Ji, A. Chaparala, E.J. Tanner, J. Chen, R.V. Davuluri, D. Matei, FTO-Dependent N (6)-Methyladenosine Modifications Inhibit Ovarian Cancer Stem Cell Self-Renewal by Blocking cAMP Signaling. Cancer research 80 (2020) 3200-3214.
[34]W.M. Henne, M.L. Reese, J.M. Goodman, The assembly of lipid droplets and their roles in challenged cells. The EMBO journal 37 (2018).
[35]L.M. Butler, Y. Perone, J. Dehairs, L.E. Lupien, V. de Laat, A. Talebi, M. Loda, W.B. Kinlaw, J.V. Swinnen, Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention. Advanced drug delivery reviews 159 (2020) 245-293.
[36]K. Tauchi-Sato, S. Ozeki, T. Houjou, R. Taguchi, T. Fujimoto, The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition. The Journal of biological chemistry 277 (2002) 44507-44512.
[37]X. van Dierendonck, M.A. de la Rosa Rodriguez, A. Georgiadi, F. Mattijssen, W. Dijk, M. van Weeghel, R. Singh, J.W. Borst, R. Stienstra, S. Kersten, HILPDA Uncouples Lipid Droplet Accumulation in Adipose Tissue Macrophages from Inflammation and Metabolic Dysregulation. Cell reports 30 (2020) 1811-1822 e1816.
[38]M. Visweswaran, F. Arfuso, S. Warrier, A. Dharmarajan, Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells. Stem Cells 38 (2020) 6-14.
[39]J. Li, S. Condello, J. Thomes-Pepin, X. Ma, Y. Xia, T.D. Hurley, D. Matei, J.X. Cheng, Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells. Cell stem cell 20 (2017) 303-314 e305.
[40]C. Giampietri, S. Petrungaro, M. Cordella, C. Tabolacci, L. Tomaipitinca, A. Facchiano, A. Eramo, A. Filippini, F. Facchiano, E. Ziparo, Lipid Storage and Autophagy in Melanoma Cancer Cells. International journal of molecular sciences 18 (2017).
[41]S.R. Singh, X. Zeng, J. Zhao, Y. Liu, G. Hou, H. Liu, S.X. Hou, The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila. Nature 538 (2016) 109-113.