Background: Urinary iodine concentration (UIC) is routinely used to evaluate the population iodine status while the uniform method for the individual level assessment is uncertain.
Objectives : To explore the 24-hour urinary iodine excretion (UIE) in five different periods of the day and the corresponding prediction equations respect by the use of creatinine-corrected UIC.
Methods: We collected 24-hour, spot and fasting urine in five periods of the day to estimate 24-hour UIE by the six different prediction equations. We compared the estimated creatinine-corrected UIC to the collected 24-hour UIE and identified the most suitable equations in each period of the day.
Results: Among the six different prediction equations, the equation of Kawasaki T was the best to estimate the 24-hour UIE by fasting urine among Chinese adults. Among the five periods of time, the equation of Knudsen N was the best to estimate the 24-hour UIE except the morning period.
Conclusion: Urinary iodine status at the individual level could be estimated by different creatinine-based equations at different periods of the day.