This paper evaluates the impacts of income inequality on life expectancy in the African countries. The empirical analysis has been performed on a panel dataset of 52 African nations covering the period of 1995-2018. For estimating the relationship, I have employed Two-Stage Least Squares (2SLS) technique and a Panel Error Correction Model (PECM). The long-run cointegrating relationship was estimated using a Panel Dynamic Ordinary Least Square (PDOLS) estimator. The outputs of both static and dynamic estimation models suggest that income inequality has negatively affected life expectancy at birth in the African continent overall. Though a positive short-run causal relationship was established, in the long-run, income inequality had deleterious effects. A series of steps had been followed to check the soundness of the result of the main empirical examination and it was confirmed that the results are robust.