This paper imitates the raised structure of the leading edge of the humpback whale fin limbs, designed six bionic blades. The aerodynamic analysis show that: the wave leading edge blade can improve the total pressure efficiency of the axial flow fan, and under off-design conditions, the aerodynamic performance of bionic fan is better than that of prototype fan. The noise analysis shows that: under the condition of constant wave number, increasing wave amplitude can reduce the overall sound pressure level at the monitoring point, in the middle and high frequency range, the sound pressure level of the bionic fan at the monitoring point is significantly lower than that of the prototype fan, and the noise reduction effect increases with the increase of wave amplitude; under the condition of constant wave amplitude, increasing the wave number can reduce the fan noise. At a certain wave number and amplitude, the overall sound pressure level of the bionic fan at the monitoring point is at most 2.91 dB lower than that of the prototype fan. In this paper, the noise reduction effect of increasing wave number is more obvious than that of increasing wave amplitude.