[1] Sun Z, Liu B, Luo ZJ. The Immune Privilege of the Intervertebral Disc: Implications for Intervertebral Disc Degeneration Treatment. INT J MED SCI 2020;5:685-92.
[2] Li HR, Cui Q, Dong ZY, Zhang JH, Li HQ, Zhao L. Downregulation of miR-27b is Involved in Loss of Type II Collagen by Directly Targeting Matrix Metalloproteinase 13 (MMP13) in Human Intervertebral Disc Degeneration. Spine (Phila Pa 1976) 2016;3:E116-23.
[3] Li Z, Chen X, Xu D, Li S, Chan M, Wu W. Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration. Cell Prolif 2019;6:e12704.
[4] Lv F, Leung VY, Huang S, Huang Y, Sun Y, Cheung KM. In search of nucleus pulposus-specific molecular markers. Rheumatology (Oxford) 2014;4:600-10.
[5] Hua WB, Wu XH, Zhang YK, et al. Dysregulated miR-127-5p contributes to type II collagen degradation by targeting matrix metalloproteinase-13 in human intervertebral disc degeneration. BIOCHIMIE 201774-80.
[6] Cao Z, Chen L. Inhibition of miR-27a suppresses the inflammatory response via the p38/MAPK pathway in intervertebral disc cells. EXP THER MED 2017;5:4572-8.
[7] Liu G, Cao P, Chen H, Yuan W, Wang J, Tang X. MiR-27a regulates apoptosis in nucleus pulposus cells by targeting PI3K. PLOS ONE 2013;9:e75251.
[8] Miyazawa K, Miyazono K. Regulation of TGF-beta Family Signaling by Inhibitory Smads. Cold Spring Harb Perspect Biol 2017;3.
[9] Sedlmeier G, Sleeman JP. Extracellular regulation of BMP signaling: welcome to the matrix. Biochem Soc Trans 2017;1:173-81.
[10] Zhu J, Zhang X, Gao W, Hu H, Wang X, Hao D. lncRNA/circRNAmiRNAmRNA ceRNA network in lumbar intervertebral disc degeneration. MOL MED REP 2019;4:3160-74.
[11] Su C, Huang DP, Liu JW, Liu WY, Cao YO. miR-27a-3p regulates proliferation and apoptosis of colon cancer cells by potentially targeting BTG1. ONCOL LETT 2019;3:2825-34.
[12] Li Z, Chen X, Xu D, Li S, Chan M, Wu W. Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration. Cell Prolif 2019;6:e12704.
[13] Penolazzi L, Lambertini E, Scussel BL, et al. Reciprocal Regulation of TRPS1 and miR-221 in Intervertebral Disc Cells. CELLS-BASEL 2019;10.
[14] Hamamura K, Lin CC, Yokota H. Salubrinal reduces expression and activity of MMP13 in chondrocytes. Osteoarthritis Cartilage 2013;5:764-72.
[15] Lian C, Gao B, Wu Z, et al. Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells. MOL MED REP 2017;4:4730-6.
[16] Cai C, Min S, Yan B, et al. MiR-27a promotes the autophagy and apoptosis of IL-1beta treated-articular chondrocytes in osteoarthritis through PI3K/AKT/mTOR signaling. Aging (Albany NY) 2019;16:6371-84.
[17] Wang Y, Cao L, Wang Q, Huang J, Xu S. LncRNA FOXD2-AS1 induces chondrocyte proliferation through sponging miR-27a-3p in osteoarthritis. Artif Cells Nanomed Biotechnol 2019;1:1241-7.
[18] Liu L, Qian H, Hu K, et al. [miR-27a-3p inhibits pulmonary fibrosis by blocking Wnt3a/beta-catenin pathway in rats]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2018;11:1015-20.
[19] Zhuang YS, Liao YY, Liu BY, et al. MicroRNA-27a mediates the Wnt/beta-catenin pathway to affect the myocardial fibrosis in rats with chronic heart failure. CARDIOVASC THER 2018e12468.
[20] Wu J, Liu S, Yuan ZW, et al. MicroRNA-27a Suppresses Detrusor Fibrosis in Streptozotocin-Induced Diabetic Rats by Targeting PRKAA2 Through the TGF-beta1/Smad3 Signaling Pathway. CELL PHYSIOL BIOCHEM 2018;4:1333-49.
[21] Li X, Xu M, Ding L, Tang J. MiR-27a: A Novel Biomarker and Potential Therapeutic Target in Tumors. J CANCER 2019;12:2836-48.
[22] Yan X, Yu H, Liu Y, Hou J, Yang Q, Zhao Y. miR-27a-3p Functions as a Tumor Suppressor and Regulates Non-Small Cell Lung Cancer Cell Proliferation via Targeting HOXB8. Technol Cancer Res Treat 20191078129619.
[23] Hu HH, Chen DQ, Wang YN, et al. New insights into TGF-beta/Smad signaling in tissue fibrosis. Chem Biol Interact 201876-83.
[24] Kuo SJ, Yang WH, Liu SC, Tsai CH, Hsu HC, Tang CH. Transforming growth factor beta1 enhances heme oxygenase 1 expression in human synovial fibroblasts by inhibiting microRNA 519b synthesis. PLOS ONE 2017;4:e176052.
[25] Li X, Guo L, Yang X, et al. TGF-beta1-induced connexin43 promotes scar formation via the Erk/MMP-1/collagen III pathway. J ORAL REHABIL 2019.
[26] Barruet E, Morales BM, Lwin W, et al. The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling. STEM CELL RES THER 2016;1:115.
[27] Li Y, Li Z, Li C, Zeng Y, Liu Y. Long noncoding RNA TM1P3 is involved in osteoarthritis by mediating chondrocyte extracellular matrix degradation. J CELL BIOCHEM 2019;8:12702-12.
[28] Hodgkinson T, Wignall F, Hoyland JA, Richardson SM. High BMPR2 expression leads to enhanced SMAD1/5/8 signalling and GDF6 responsiveness in human adipose-derived stem cells: implications for stem cell therapies for intervertebral disc degeneration. J TISSUE ENG 20201542318554.
[29] Wang Z, Fu C, Chen Y, et al. FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc. PLOS ONE 2016;1:e147764.