Research Articleposted 2024-09-02 13:09:27
IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas
Gulce Sari, Karthik Dhatchinamoorthy, Laura Orellano-Ariza, Lindsay M Ferreira, Michael A. Brehm, Kenneth Rock
Published
at
Research Articleposted 2024-03-13 16:13:54
Integrin-linked kinase-frizzled 7 interaction maintains cancer stem cells to drive platinum resistance in ovarian cancer
Rula Atwani, Amber Rogers, Rohit Nagare, Mayuri Prasad, Virginie Lazar, George Sandusky, Fabrizio Pin, and 1 more authors
Published
at
Research Articleposted 2024-02-15 15:56:57
Hypoxia-enhanced YAP1-EIF4A3 interaction drives circ_0007386 circularization by competing with CRIM1 pre-mRNA linear splicing and promotes non-small cell lung cancer progression
Lixia Li, Dewei Liu, Tingting Chen, Chunhui Wei, Youping Qiao, Weiliang Liu, Yanmei Liang, and 7 more authors
Published
at
Research Articleposted 2024-02-06 17:04:46
Bispecific aptamer-decorated and light-triggered nanoparticles targeting tumor and stromal cells in breast cancer derived organoids: implications for precision phototherapies
Simona Camorani, Alessandra Caliendo, Elena Morrone, Lisa Agnello, Matteo Martini, Monica Cantile, Margherita Cerrone, and 5 more authors
Published
at
Research Articleposted 2024-02-02 06:11:35
Identification of genetic modifiers enhancing B7-H3-targeting CAR T cell therapy against glioblastoma through large-scale CRISPRi screening
Xing Li, Shiyu Sun, Wansong Zhang, Ziwei Liang, Yitong Fang, Tianhu Sun, Yong Wan, and 4 more authors
Published
at
Research Articleposted 2024-01-04 07:48:48
IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis
Kaifan Yang, Yanjun Hu, Yuanyuan Feng, Kaiqun Li, Ziyan Zhu, Shuyi Liu, Yanling Lin, and 1 more authors
Published
at
Research Articleposted 2024-01-01 09:48:41
PRMT6-mediated Transcriptional Activation of YTHDF2 Promotes Glioblastoma Migration, Invasion, and EMT via the Wnt–β-Catenin Pathway
Peng Yu, Tutu Xu, Wenmeng Ma, Xiang Fang, Yue Bao, Chengran Xu, Jinhai Huang, and 2 more authors
Published
at
Research Articleposted 2023-12-28 14:54:25
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
Anneta Brousali, Jeanine M. Roodhart, Sylvia F. Boj, Onno Kranenburg, Robert G. Vries, Sjoerd G. Elias, Bas Penning de Vries, and 13 more authors
Published
at
Research Articleposted 2023-12-23 16:01:03
Targeting mTOR and Survivin Concurrently Potentiates Radiation Therapy in Renal Cell Carcinoma by Suppressing DNA Damage Repair and Amplifying Mitotic Catastrophe
Hari K. Rachamala, Vijay S. Madamsetty, Ramcharan S. Angom, Naga M. Nakka, Shamit Kumar Dutta, Enfeng Wang, Debabrata Mukhopadhyay, and 1 more authors
Under Review
at
Research Articleposted 2023-12-15 17:28:12
Suppression of hypoxia-induced stemness and chemoresistance in ovarian tumors
Sandra Munoz-Galvan, Eva M. Verdugo-Sivianes, José M. Santos-Pereira, Purificación Estevez-García, Amancio Carnero
Published
at