Identification and characterization of binders to a novel cryptic and functional pocket in KRAS
The alternative NF-κB RelB subunit is a novel critical sensor of lipid metabolism to promote tumor development
Mevalonate kinase inhibits anti-tumor immunity by impairing the tumor cell-intrinsic interferon response in microsatellite instability colorectal cancer
The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells
KRT23 acts as an oncogene in hepatocellular carcinoma by regulating PI3K/AKT/GSK3β pathway via P21
The m6A reader IGF2BP3 promotes LIHC progression by enhancing MCM10 stability
MECOM promotes leukemia progression and inhibits mast cell differentiation through functional competition with GATA2
CXCL7 plays a crucial role in facilitating extramedullary invasion and osteolytic damage in multiple myeloma
Elucidation of the mechanism of c-Myc expression in invasive ductal breast cancer using fluorescence in situ hybridization
CDK9 recruits HUWE1 E3 ligase to degrade RARα in a kinase independent manner and offers therapeutic opportunities for cutaneous T-cell lymphoma