Articleposted 2024-10-24 04:01:18
Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis
M. Cromer, Aadit Shah, Kiran Majeti, Freja Ekman, Sridhar Selvaraj, Devesh Sharma, Roshani Sinha, and 9 more authors
Under Review
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Articleposted 2024-01-26 19:40:54
Targeting mosquito X-chromosomes reveals complex transmission dynamics of sex ratio distorting gene drives
Philippos Papathanos, Daniella Haber, Yael Arien, Lee Lamdan, Yehonathan Alcalay, Chen Zecharia, Flavia Krsticevic, and 6 more authors
Published
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Articleposted 2023-12-01 21:35:08
Homing-based gene drives can introgress rapidly into local genetic backgrounds with minimal chromosomal conversion in Anopheles gambiae
Tony Nolan, Poppy Pescod, Giulia Bevivino, Amalia Anthousi, Josephine Shepherd, Ruth Shelton, Fabrizio Lombardo
Published
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Articleposted 2023-07-27 14:23:07
p38 MAPK fuels proliferation stress and DNA damage impairing the functionality of genetically engineered hematopoietic stem and progenitor cells
Giacomo Farina, Luigi Naldini, Bernhard Gentner, Ivan Merelli, Anastasia Conti, Diego Gilioli, Angelica Varesi, and 13 more authors
Posted
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Articleposted 2023-07-18 22:31:26
Genome-wide genetic mutations accumulated in genome-edited pigs and their filial generation for xenotransplantation
Changlong Li, Chen Zhang, Shunmin He, Dengke Pan, Zhenwen Chen, Xin Liu, Lixue Cao, and 10 more authors
Posted
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Articleposted 2023-06-22 20:54:50
CRISPR-based gene drives generate super-Mendelian inheritance in the disease vector Culex quinquefasciatus.
Tim Harvey-Samuel, Xuechun Feng, Emily Okamoto, Deepak-Kumar Purusothaman, Philip Leftwich, Luke Alphey, Valentino Gantz
Published
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Articleposted 2023-03-17 20:34:53
Transient Inhibition of 53BP1 Increases the Frequency of Targeted Integration in Human Hematopoietic Stem and Progenitor Cells
Ron Baik, M Cromer, Steve Glenn, Christopher Vakulskas, Amanda Dudek, William Feist, Suzette Shipp, and 2 more authors
Published
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Articleposted 2023-02-17 20:45:14
Shuttle Peptide Delivers Base Editor RNPs to Rhesus Monkey Airway Epithelial Cells In Vivo
Katarina Kulhankova, Soumba Traore, Xue Cheng, Hadrien Benk-Fortin, Stéphanie Hallée, Mario Harvey, Joannie Roberge, and 7 more authors
Published
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Articleposted 2023-01-25 06:21:27
OPED: an optimal prime editing guide RNA designer based on deep learning and transfer learning
Wenjie Shu, Feng Liu, Shuhong Huang, Jiongsong Hu, Xiaozhou Chen, Ziguo Song, Junguo Dong, and 4 more authors
Published
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Articleposted 2021-03-18 16:58:59
Amelioration of hemophilia B through CRISPR/Cas9 induced homology-independent targeted integration
Yanjiao Shao, Xiaohui Zhang, Jiazhi Hu, Mingyao Liu, Fengxiang Jing, Meizhen Liu, Xueyun Ma, and 12 more authors
Posted
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