Operating principles of coupled feedback networks driving cell fate transitions
Gene Regulatory Network topology mediates the role of diffusible components in cellular patterns: the root epidermis of Arabidopsis thaliana as a study system
Simplifications and approximations in molecular systems biology: lessons from a single-gene circuit
A mathematical-computational model explains phenotypic plasticity changes by mutations underlying hepatic cancer stem cells emergence
Mathematical Model of the Human Inflammatory Response to Acute and Prolonged Lipopolysaccharide Exposure
Novel brain-penetrant inhibitor of G9a methylase blocks Alzheimer’s disease proteopathology for precision medication
T-cell commitment inheritance – an agent-based multi-scale model
Multi-omic data and modelling analyses reveal that HAP complex integrates TORC1/PKA and SNF1 signalling pathways
Distinct patterns of proteostasis network gene expression are associated with different prognoses in melanoma patients
In vivo RNA interactome profiling reveals 3’UTR-processed small RNA targeting a central regulatory hub