Background: This study evaluated short-term changes in intraocular pressure (IOP) and corneal thickness (CCT) following haemodialysis (HD) in chronic renal failure (CRF) patients.
Methods: We studied 34 eyes of 34 patients with CRF undergoing HD. Patients included in the study were classified into two subgroups: group 1 (with DM) and group 2 (non DM). All patients underwent a detailed ophthalmological examination including CCT and IOP before and after the HD session. Total body weight and body volume loss after haemodialysis were also measured.
Results: The sex distribution of patients were 22 female (64.7%) and 12 male (35.3%). The DM group was comprised of 19 patients (55.9%), and the non-DM had 15 (44.1%). The mean age was 60.3 ± 17.2 (range 21–88) years, and the dialysis time was 51.4 ± 38.5 (range 5–132) months. The mean IOP change after HD decreased from 15.88±2.37 to 14.11±2.02 mmHg (95% CI, 1.40–2.11; p < 0.001). The mean CCT decreased from 554.88±14.27 to 550.52±13.67 μm. (95% CI, 1.97–4.08; P = p < 0.001). The loss in body volume was positively correlated with a decrease in IOP (r = 0.737, p < 0.001) and CCT (r = 0.784, p < 0.001).
Conclusions: In patients with CRF who have glaucoma, visual acuity may be adversely affected by IOP and CCT changes following HD. Therefore, a detailed ophthalmologic examination should be performed to take preventive measures for at-risk patients before and after HD.
Keywords: Hemodialysis, Intraocular pressure, Central Corneal thickness.