Aim
The synthesis of nanosilver particles (AgNPs) from Pelargonium quercetorum Agnew. (Geraniaceae) and evaluation of the antimicrobial and the cytotoxic potential of AgNPs.
Materials & Methods
The synthesized AgNPs were evaluated for antimicrobial and anticancer efficacy using the minimum inhibition concentration method and MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide) assay.
Results
The AgNPs inhibited approximately 90% the growth of gram-positive Staphylococcus aureus and gram-negative Esherichia coli and yeast Candida albicans pathogens at a concentration of 500 µg/mL. The synthesized AgNPs showed excellent toxicity in MCF-7 cells, and specifically, pq70 AgNP inhibited the growth of MCF-7 cells by 52% at a concentration of 3.125 µg/mL.
Conclusion
It was determined that the AgNPs, which had been synthesized from extracts that contained a high phenolic composition, were smaller in size, and showed high anticancer and antimicrobial properties.
Figure 1
Figure 2
Figure 3
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Posted 26 Mar, 2021
Received 12 Apr, 2021
Received 12 Apr, 2021
On 11 Apr, 2021
On 06 Apr, 2021
On 29 Mar, 2021
Invitations sent on 23 Mar, 2021
On 23 Mar, 2021
On 23 Mar, 2021
On 23 Mar, 2021
On 16 Mar, 2021
Posted 26 Mar, 2021
Received 12 Apr, 2021
Received 12 Apr, 2021
On 11 Apr, 2021
On 06 Apr, 2021
On 29 Mar, 2021
Invitations sent on 23 Mar, 2021
On 23 Mar, 2021
On 23 Mar, 2021
On 23 Mar, 2021
On 16 Mar, 2021
Aim
The synthesis of nanosilver particles (AgNPs) from Pelargonium quercetorum Agnew. (Geraniaceae) and evaluation of the antimicrobial and the cytotoxic potential of AgNPs.
Materials & Methods
The synthesized AgNPs were evaluated for antimicrobial and anticancer efficacy using the minimum inhibition concentration method and MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide) assay.
Results
The AgNPs inhibited approximately 90% the growth of gram-positive Staphylococcus aureus and gram-negative Esherichia coli and yeast Candida albicans pathogens at a concentration of 500 µg/mL. The synthesized AgNPs showed excellent toxicity in MCF-7 cells, and specifically, pq70 AgNP inhibited the growth of MCF-7 cells by 52% at a concentration of 3.125 µg/mL.
Conclusion
It was determined that the AgNPs, which had been synthesized from extracts that contained a high phenolic composition, were smaller in size, and showed high anticancer and antimicrobial properties.
Figure 1
Figure 2
Figure 3
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