See the published version of this preprint at Lipids in Health and Disease.
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Danhong Fang
Wenzhou Medical University First Affiliated Hospital
Corresponding Author
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Background In a previous study, the high ratio of serum triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) was relevant to a high risk of sarcopenia in Korean old males. In this study, the purpose was to discover the correlation in Chinese community adults.
Methods Chinese adults who had physical examinations from May 2016 to August 2017 at the First Affiliated Hospital of Wenzhou Medical University were involved in this study. The univariable and multivariable analyses were applied to evaluate possible effect and an association was found in a subgroup analysis.
Results In total, 2613 adults were involved in the study, with 13.85% presenting sarcopenia. Individuals with TG/HDL-C ratios <2.78 or ≥2.78 were categorized as TG/HDL-Clow or TG/HDL-Chigh, respectively. 1266 individuals were in high group and the remaining were in the low group. By univariate and multivariable analyses, the ratio of TG/HDL-C remained independent association with sarcopenia status(OR: 0.63; 95%CI: 0.49-0.81). Besides, the effect of the TG/HDL-C ratio kept significantly favorable (OR<1.00) in most subgroups, except in groups aged＞65 years and in the overweight population.
Conclusions The negative correlation between sarcopenia and TG/HDL-C ratio was discovered in Chinese community population, particularly in subjects aged <65 years and in non-overweight population.
Keywords
sarcopenia, triglyceride, high-density lipoprotein cholesterol, Chinese community adults
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CURRENT STATUS: Published
View the published article at Lipids in Health and Disease.
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Editorial decision: Accept
On 19 Nov, 2020
Editor assigned
On 08 Nov, 2020
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On 08 Nov, 2020
Editor invited
On 08 Nov, 2020
No comments provided
Editorial decision: Moderate Revision
On 29 Oct, 2020
Editor assigned
On 09 Oct, 2020
Submission checks complete
On 08 Oct, 2020
Editor invited
On 08 Oct, 2020
No comments provided
Editorial decision: Moderate Revision
On 29 Sep, 2020
Editor assigned
On 28 Sep, 2020
Submission checks complete
On 27 Sep, 2020
Editor invited
On 27 Sep, 2020
No comments provided
Editorial decision: Moderate Revision
On 18 Sep, 2020
Reviewer #2 agreed
On 13 Sep, 2020
Review #2 received
Received 13 Sep, 2020
Review #1 received
Received 11 Sep, 2020
Reviewers invited
Invitations sent on 10 Sep, 2020
Reviewer #1 agreed
On 10 Sep, 2020
Editor assigned
On 06 Sep, 2020
Submission checks complete
On 05 Sep, 2020
Editor invited
On 05 Sep, 2020
Version 2
Posted 19 Aug, 2020
No comments provided
Editorial decision: Major revision
On 27 Aug, 2020
Review #3 received
Received 24 Aug, 2020
Reviewer #4 agreed
On 21 Aug, 2020
Review #4 received
Received 21 Aug, 2020
Reviewer #3 agreed
On 20 Aug, 2020
Reviewer #1 agreed
On 17 Aug, 2020
Reviewer #2 agreed
On 17 Aug, 2020
Review #2 received
Received 17 Aug, 2020
Review #1 received
Received 17 Aug, 2020
Editor assigned
On 17 Aug, 2020
Reviewers invited
Invitations sent on 17 Aug, 2020
Submission checks complete
On 16 Aug, 2020
Editor invited
On 16 Aug, 2020
No comments provided
Editorial decision: Major revision
On 22 Jul, 2020
Review #3 received
Received 13 Jul, 2020
Review #4 received
Received 13 Jul, 2020
Reviewer #4 agreed
On 06 Jul, 2020
Review #2 received
Received 06 Jul, 2020
Reviewer #3 agreed
On 05 Jul, 2020
Reviewer #2 agreed
On 05 Jul, 2020
Reviewer #1 agreed
On 25 Jun, 2020
Review #1 received
Received 25 Jun, 2020
Reviewers invited
Invitations sent on 24 Jun, 2020
First submitted
On 18 Jun, 2020
Editor assigned
On 18 Jun, 2020
Submission checks complete
On 17 Jun, 2020
Editor invited
On 17 Jun, 2020
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See the published version of this preprint at Lipids in Health and Disease.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Danhong Fang
Wenzhou Medical University First Affiliated Hospital
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Lipids in Health and Disease.
No community comments so far
Editorial decision: Accept
On 19 Nov, 2020
Editor assigned
On 08 Nov, 2020
Submission checks complete
On 08 Nov, 2020
Editor invited
On 08 Nov, 2020
No comments provided
Editorial decision: Moderate Revision
On 29 Oct, 2020
Editor assigned
On 09 Oct, 2020
Submission checks complete
On 08 Oct, 2020
Editor invited
On 08 Oct, 2020
No comments provided
Editorial decision: Moderate Revision
On 29 Sep, 2020
Editor assigned
On 28 Sep, 2020
Submission checks complete
On 27 Sep, 2020
Editor invited
On 27 Sep, 2020
No comments provided
Editorial decision: Moderate Revision
On 18 Sep, 2020
Reviewer #2 agreed
On 13 Sep, 2020
Review #2 received
Received 13 Sep, 2020
Review #1 received
Received 11 Sep, 2020
Reviewers invited
Invitations sent on 10 Sep, 2020
Reviewer #1 agreed
On 10 Sep, 2020
Editor assigned
On 06 Sep, 2020
Submission checks complete
On 05 Sep, 2020
Editor invited
On 05 Sep, 2020
Version 2
Posted 19 Aug, 2020
No comments provided
Editorial decision: Major revision
On 27 Aug, 2020
Review #3 received
Received 24 Aug, 2020
Reviewer #4 agreed
On 21 Aug, 2020
Review #4 received
Received 21 Aug, 2020
Reviewer #3 agreed
On 20 Aug, 2020
Reviewer #1 agreed
On 17 Aug, 2020
Reviewer #2 agreed
On 17 Aug, 2020
Review #2 received
Received 17 Aug, 2020
Review #1 received
Received 17 Aug, 2020
Editor assigned
On 17 Aug, 2020
Reviewers invited
Invitations sent on 17 Aug, 2020
Submission checks complete
On 16 Aug, 2020
Editor invited
On 16 Aug, 2020
No comments provided
Editorial decision: Major revision
On 22 Jul, 2020
Review #3 received
Received 13 Jul, 2020
Review #4 received
Received 13 Jul, 2020
Reviewer #4 agreed
On 06 Jul, 2020
Review #2 received
Received 06 Jul, 2020
Reviewer #3 agreed
On 05 Jul, 2020
Reviewer #2 agreed
On 05 Jul, 2020
Reviewer #1 agreed
On 25 Jun, 2020
Review #1 received
Received 25 Jun, 2020
Reviewers invited
Invitations sent on 24 Jun, 2020
First submitted
On 18 Jun, 2020
Editor assigned
On 18 Jun, 2020
Submission checks complete
On 17 Jun, 2020
Editor invited
On 17 Jun, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Lipids in Health and Disease.
Background In a previous study, the high ratio of serum triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) was relevant to a high risk of sarcopenia in Korean old males. In this study, the purpose was to discover the correlation in Chinese community adults.
Methods Chinese adults who had physical examinations from May 2016 to August 2017 at the First Affiliated Hospital of Wenzhou Medical University were involved in this study. The univariable and multivariable analyses were applied to evaluate possible effect and an association was found in a subgroup analysis.
Results In total, 2613 adults were involved in the study, with 13.85% presenting sarcopenia. Individuals with TG/HDL-C ratios <2.78 or ≥2.78 were categorized as TG/HDL-Clow or TG/HDL-Chigh, respectively. 1266 individuals were in high group and the remaining were in the low group. By univariate and multivariable analyses, the ratio of TG/HDL-C remained independent association with sarcopenia status(OR: 0.63; 95%CI: 0.49-0.81). Besides, the effect of the TG/HDL-C ratio kept significantly favorable (OR<1.00) in most subgroups, except in groups aged＞65 years and in the overweight population.
Conclusions The negative correlation between sarcopenia and TG/HDL-C ratio was discovered in Chinese community population, particularly in subjects aged <65 years and in non-overweight population.
Figure 1
Figure 2
This is a list of supplementary files associated with this preprint. Click to download.
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