Abdanipour, A., Tiraihi, T., and Delshad, A. (2011). Trans-differentiation of the adipose tissue-derived stem cells into neuron-like cells expressing neurotrophins by selegiline. Iran Biomed J 15, 113-121.
Albers, G.W., Diener, H.C., Grind, M., Halperin, J.L., Horrow, J., Olsson, S.B., Petersen, P., Vahanian, A., Frison, L., Nevinson, M., et al. (2003). Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial. Lancet 362, 1691-1698.
Blecker, D., Elashry, M.I., Heimann, M., Wenisch, S., and Arnhold, S. (2017). New Insights into the Neural Differentiation Potential of Canine Adipose Tissue-Derived Mesenchymal Stem Cells. Anat Histol Embryol 46, 304-315.
Burrow, K.L., Hoyland, J.A., and Richardson, S.M. (2017). Human Adipose-Derived Stem Cells Exhibit Enhanced Proliferative Capacity and Retain Multipotency Longer than Donor-Matched Bone Marrow Mesenchymal Stem Cells during Expansion In Vitro. Stem Cells Int 2017.
Chen, A.Z., Liu, N., Huang, H., Lin, F.F., Liu, D.S., and Lin, X.H. (2011). [Outgrowth of neuronal axons on adipose-derived stem cell transplanting for treatment of cerebral infarction in rats]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 27, 868-871.
Chen, J.Y., Gu, Z.J., Wu, M.X., Yang, Y., Zhang, J.H., Ou, J.S., Zuo, Z.Y., Wang, J.F., and Chen, Y.X. (2016). C-reactive protein can upregulate VEGF expression to promote ADSC-induced angiogenesis by activating HIF-1 alpha via CD64/PI3k/Akt and MAPK/ERK signaling pathways. Stem Cell Research & Therapy 7.
Cheng, F., Lu, X.C., Hao, H.Y., Dai, X.L., Da Qian, T., Huang, B.S., Tang, L.J., Yu, W., and Li, L.X. (2014). Neurogenin 2 Converts Mesenchymal Stem Cells into a Neural Precursor Fate and Improves Functional Recovery after Experimental Stroke. Cellular Physiology and Biochemistry 33, 847-858.
Chi, K., Fu, R.H., Huang, Y.C., Chen, S.Y., Hsu, C.J., Lin, S.Z., Tu, C.T., Chang, L.H., Wu, P.A., and Liu, S.P. (2018). Adipose-derived Stem Cells Stimulated with n-Butylidenephthalide Exhibit Therapeutic Effects in a Mouse Model of Parkinson's Disease. Cell Transplant 27, 456-470.
Ciervo, Y., Ning, K., Jun, X., Shaw, P.J., and Mead, R.J. (2017). Advances, challenges and future directions for stem cell therapy in amyotrophic lateral sclerosis. Mol Neurodegener 12.
Danielyan, L., Schafer, R., von Ameln-Mayerhofer, A., Bernhard, F., Verleysdonk, S., Buadze, M., Lourhmati, A., Klopfer, T., Schaumann, F., Schmid, B., et al. (2011). Therapeutic Efficacy of Intranasally Delivered Mesenchymal Stem Cells in a Rat Model of Parkinson Disease. Rejuv Res 14, 3-16.
De Miguel, M.P., Fuentes-Julian, S., Blazquez-Martinez, A., Pascual, C.Y., Aller, M.A., Arias, J., and Arnalich-Montiel, F. (2012). Immunosuppressive Properties of Mesenchymal Stem Cells: Advances and Applications. Curr Mol Med 12, 574-591.
Diederich, K., Schmidt, A., Strecker, J.K., Schabitz, W.R., Schilling, M., and Minnerup, J. (2014). Cortical Photothrombotic Infarcts Impair the Recall of Previously Acquired Memories but Spare the Formation of New Ones. Stroke 45, 614-618.
Diez-Tejedor, E., Gutierrez-Fernandez, M., Martinez-Sanchez, P., Rodriguez-Frutos, B., Ruiz-Ares, G., Lara, M.L., and Gimeno, B.F. (2014). Reparative Therapy for Acute Ischemic Stroke with Allogeneic Mesenchymal Stem Cells from Adipose Tissue: A Safety Assessment A Phase II Randomized, Double-blind, Placebo-controlled, Single-center, Pilot Clinical Trial. J Stroke Cerebrovasc 23, 2694-2700.
Du, W.J., Reppel, L., Leger, L., Schenowitz, C., Huselstein, C., Bensoussan, D., Carosella, E.D., Han, Z.C., and Rouas-Freiss, N. (2016). Mesenchymal Stem Cells Derived from Human Bone Marrow and Adipose Tissue Maintain Their Immunosuppressive Properties After Chondrogenic Differentiation: Role of HLA-G. Stem Cells Dev 25, 1454-1469.
Dulamea, A.O. (2015). The potential use of mesenchymal stem cells in stroke therapy-From bench to bedside. J Neurol Sci 352, 1-11.
Duma, C., Kopyov, O., Kopyov, A., Berman, M., Lander, E., Elam, M., Arata, M., Weiland, D., Cannell, R., Caraway, C., et al. (2019). Human intracerebroventricular (ICV) injection of autologous, non-engineered, adipose-derived stromal vascular fraction (ADSVF) for neurodegenerative disorders: results of a 3-year phase 1 study of 113 injections in 31 patients. Mol Biol Rep 46, 5257-5272.
Ehrenreich, H., Weissenborn, K., Prange, H., Schneider, D., Weimar, C., Wartenberg, K., Schellinger, P.D., Bohn, M., Becker, H., Wegrzyn, M., et al. (2009). Recombinant Human Erythropoietin in the Treatment of Acute Ischemic Stroke. Stroke 40, E647-E656.
Falnikar, A., Li, K., and Lepore, A.C. (2015). Therapeutically targeting astrocytes with stem and progenitor cell transplantation following traumatic spinal cord injury. Brain Res 1619, 91-103.
Feng, N.H., Jia, Y.J., and Huang, X.X. (2019). Exosomes from adipose-derived stem cells alleviate neural injury caused by microglia activation via suppressing NF-kB and MAPK pathway. J Neuroimmunol 334.
Gao, S., Zhao, P., Lin, C., Sun, Y.X., Wang, Y.L., Zhou, Z.C., Yang, D.J., Wang, X.L., Xu, H.Z., Zhou, F., et al. (2014). Differentiation of Human Adipose-Derived Stem Cells into Neuron-Like Cells Which Are Compatible with Photocurable Three-Dimensional Scaffolds. Tissue Eng Pt A 20, 1271-1284.
Gao, S.N., Guo, X.X., Zhao, S.M., Jin, Y.P., Zhou, F., Yuan, P., Cao, L.M., Wang, J., Qiu, Y., Sun, C.X., et al. (2019). Differentiation of human adipose-derived stem cells into neuron/motoneuron-like cells for cell replacement therapy of spinal cord injury. Cell Death Dis 10.
Gomez-de Frutos, M.C., Laso-Garcia, F., Diekhorst, L., Otero-Ortega, L., Fuentes, B., Jolkkonen, J., Detante, O., Moisan, A., Martinez-Arroyo, A., Diez-Tejedor, E., et al. (2019). Intravenous delivery of adipose tissue-derived mesenchymal stem cells improves brain repair in hyperglycemic stroke rats. Stem Cell Research & Therapy 10.
Gon, B., Dong, Y.P., He, C., Jiang, W.W., Shan, Y., Zhou, B.Y., and Li, W.F. (2019). Intravenous Transplants of Human Adipose-Derived Stem Cell Protect the Rat Brain From Ischemia-Induced Damage. J Stroke Cerebrovasc 28, 595-603.
Guo, X.L., Wang, X., Li, Y., Zhou, B., Chen, W.D., and Ren, L.H. (2019). Olfactory ensheathing cell transplantation improving cerebral infarction sequela: a case report and literature review. J Neurorestoratology 7, 82-88.
Han, C., Zhang, L., Song, L., Liu, Y., Zou, W., Piao, H., and Liu, J. (2014). Human adipose-derived mesenchymal stem cells: a better cell source for nervous system regeneration. Chinese Med J-Peking 127, 329-337.
Hao, R., Qi, Y., Hou, D.N., Ji, Y.Y., Zheng, C.Y., Li, C.Y., Yung, W.H., Lu, B., and Huang, Y. (2017). BDNF val66met Polymorphism Impairs Hippocampal Long-Term Depression by Down-Regulation of 5-HT3 Receptors. Front Cell Neurosci 11.
Huang, H.Y., Chen, L., Mao, G.S., and Sharma, H.S. (2020). Clinical neurorestorative cell therapies: Developmental process, current state and future prospective. J Neurorestoratology 8, 61-82.
Huang, Y., Ko, H., Cheung, Z.H., Yung, K.K.L., Yao, T., Wang, J.J., Morozov, A., Ke, Y., Ip, N.Y., and Yung, W.H. (2012). Dual actions of brain-derived neurotrophic factor on GABAergic transmission in cerebellar Purkinje neurons. Exp Neurol 233, 791-798.
Huang, Y., Yoon, K., Ko, H., Jiao, S., Ito, W., Wu, J.Y., Yung, W.H., Lu, B., and Morozov, A. (2016). 5-HT3a Receptors Modulate Hippocampal Gamma Oscillations by Regulating Synchrony of Parvalbumin-Positive Interneurons. Cereb Cortex 26, 576-585.
Imamura, H., Adachi, T., Kin, T., Ono, S., Sakai, Y., Adachi, T., Soyama, A., Hidaka, M., Takatsuki, M., Shapiro, A.M.J., et al. (2018). An engineered cell sheet composed of human islets and human fibroblast, bone marrow-derived mesenchymal stem cells, or adipose-derived mesenchymal stem cells: An in vitro comparison study. Islets 10.
Jahan, R., Saver, J.L., Schwamm, L.H., Fonarow, G.C., Liang, L., Matsouaka, R.A., Xian, Y., Holmes, D.N., Peterson, E.D., Yavagal, D., et al. (2019). Association Between Time to Treatment With Endovascular Reperfusion Therapy and Outcomes in Patients With Acute Ischemic Stroke Treated in Clinical Practice. Jama-J Am Med Assoc 322, 252-263.
Jeong, C.H., Kim, S.M., Lim, J.Y., Ryu, C.H., Jun, J.A., and Jeun, S.S. (2014). Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model. Biomed Res Int 2014.
Jeong, H.H., Piao, S., Ha, J.N., Kim, I.G., Oh, S.H., Lee, J.H., Cho, H.J., Hong, S.H., Kim, S.W., and Lee, J.Y. (2013). Combined Therapeutic Effect of Udenafil and Adipose-derived Stem Cell (ADSC)/Brain-derived Neurotrophic Factor (BDNF)-Membrane System in a Rat Model of Cavernous Nerve Injury. Urology 81.
Kim, J.H., Choi, S.C., Park, C.Y., Park, J.H., Choi, J.H., Joo, H.J., Hong, S.J., and Lim, D.S. (2016). Transplantation of Immortalized CD34+and CD34-Adipose-Derived Stem Cells Improve Cardiac Function and Mitigate Systemic Pro-Inflammatory Responses. Plos One 11.
Kim, J.M., Lee, S.T., Chu, K., Jung, K.H., Song, E.C., Kim, S.J., Sinn, D.I., Kim, J.H., Park, D.K., Kang, K.M., et al. (2007). Systemic transplantation of human adipose stem cells attenuated cerebral inflammation and degeneration in a hemorrhagic stroke model. Brain Res 1183, 43-50.
Kim, S., Chang, K.A., Kim, J.A., Park, H.G., Ra, J.C., Kim, H.S., and Suh, Y.H. (2012). The Preventive and Therapeutic Effects of Intravenous Human Adipose-Derived Stem Cells in Alzheimer's Disease Mice. Plos One 7.
Kuhbier, J.W., Weyand, B., Radtke, C., Vogt, P.M., Kasper, C., and Reimers, K. (2010). Isolation, Characterization, Differentiation, and Application of Adipose-Derived Stem Cells. Adv Biochem Eng Biot 123, 55-105.
Kuzma-Kozakiewicz, M., Marchel, A., Kaminska, A., Gawel, M., Sznajder, J., Figiel-Dabrowska, A., Nowak, A., Maj, E., Krzesniak, N.E., Noszczyk, B.H., et al. (2018). Intraspinal Transplantation of the Adipose Tissue-Derived Regenerative Cells in Amyotrophic Lateral Sclerosis in Accordance with the Current Experts' Recommendations: Choosing Optimal Monitoring Tools. Stem Cells Int 2018.
Lee, M., Ban, J.J., Kim, K.Y., Jeon, G.S., Im, W., Sung, J.J., and Kim, M. (2016). Adipose-derived stem cell exosomes alleviate pathology of amyotrophic lateral sclerosis in vitro. Biochem Bioph Res Co 479, 434-439.
Lee, M., Ban, J.J., Yang, S., Im, W., and Kim, M. (2018). The exosome of adipose-derived stem cells reduces beta-amyloid pathology and apoptosis of neuronal cells derived from the transgenic mouse model of Alzheimer's disease. Brain Res 1691, 87-93.
Leu, S., Lin, Y.C., Yuen, C.M., Yen, C.H., Kao, Y.H., Sun, C.K., and Yip, H.K. (2010). Adipose-derived mesenchymal stem cells markedly attenuate brain infarct size and improve neurological function in rats. J Transl Med 8.
Li, X., Zheng, W., Bai, H.Y., Wang, J., Wei, R.L., Wen, H.T., and Ning, H.B. (2016). Intravenous administration of adipose tissue-derived stem cells enhances nerve healing and promotes BDNF expression via the TrkB signaling in a rat stroke model. Neuropsych Dis Treat 12, 1287-1293.
Liberale, L., Gaul, D.S., Akhmedov, A., Bonetti, N.R., Nageswaran, V., Costantino, S., Pahla, J., Weber, J., Fehr, V., Vdovenko, D., et al. (2020). Endothelial SIRT6 blunts stroke size and neurological deficit by preserving blood-brain barrier integrity: a translational study. Eur Heart J 41, 1575-1587.
Luo, H.L., Zhang, Y.J., Zhang, Z.Q., and Jin, Y. (2012). The protection of MSCs from apoptosis in nerve regeneration by TGF beta 1 through reducing inflammation and promoting VEGF-dependent angiogenesis. Biomaterials 33, 4277-4287.
Lyden, P., Shuaib, A., Ng, K., Levin, K., Atkinson, R.P., Rajput, A., Wechsler, L., Ashwood, T., Claesson, L., Odergren, T., et al. (2002). Clomethiazole Acute Stroke Study in ischemic stroke (CLASS-I) - Final results. Stroke 33, 122-128.
Morris, G.F., Bullock, R., Marshall, S.B., Marmarou, A., Maas, A., Marshall, L.F., and Investigators, S. (1999). Failure of the competitive N-methyl-D-aspartate antagonist Selfotel (CGS 19755) in the treatment of severe head injury: results of two Phase III clinical trials. J Neurosurg 91, 737-743.
Peng, W., Gao, T.J., Yang, Z.L., Zhang, S.C., Ren, M.L., Wang, Z.G., and Zhang, B. (2012). Adipose-derived stem cells induced dendritic cells undergo tolerance and inhibit Th1 polarization. Cell Immunol 278, 152-157.
Qin, Y.R., Zhou, C.K., Wang, N.H., Yang, H., and Gao, W.Q. (2015). Conversion of Adipose Tissue-Derived Mesenchymal Stem Cells to Neural Stem Cell-Like Cells by a Single Transcription Factor, Sox2. Cellular Reprogramming 17, 221-226.
Radhakrishnan, S., Trentz, O.A., Reddy, M.S., Rela, M., Kandasamy, M., and Sellathamby, S. (2019). In vitro transdifferentiation of human adipose tissue-derived stem cells to neural lineage cells-a stage-specific incidence. Adipocyte 8, 164-177.
Reid, A.J., Sun, M., Wiberg, M., Downes, S., Terenghi, G., and Kingham, P.J. (2011). Nerve Repair with Adipose-Derived Stem Cells Protects Dorsal Root Ganglia Neurons from Apoptosis. Neuroscience 199, 515-522.
Romanov, Y.A., Darevskava, A.N., Merzlikina, N.V., and Buravkova, L.B. (2005). Mesenchymal stem cells from human bone marrow and adipose tissue: Isolation, characterization, and differentiation potentialities. B Exp Biol Med+ 140, 138-143.
Russell, K.A., Chow, N.H.C., Dukoff, D., Gibson, T.W.G., LaMarre, J., Bette, D.H., and Koch, T.G. (2016). Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells. Plos One 11.
Schmidt, A., Diederich, K., Strecker, J.K., Geng, B., Hoppen, M., Duning, T., Schabitz, W.R., and Minnerup, J. (2015). Progressive Cognitive Deficits in a Mouse Model of Recurrent Photothrombotic Stroke. Stroke 46, 1127-+.
Sherman, D.G., Bes, A., Easton, J.D., Hacke, W., Kaste, M., Polmar, S.H., Zivin, J.A., Fieschi, C., Miller, P., Schoenfeld, D., et al. (2001). Use of anti-ICAM-1 therapy in ischemic stroke - Results of the Enlimomab Acute Stroke Trial. Neurology 57, 1428-1434.
Tobin, M.K., Bonds, J.A., Minshall, R.D., Pelligrino, D.A., Testai, F.D., and Lazarov, O. (2014). Neurogenesis and inflammation after ischemic stroke: what is known and where we go from here. J Cerebr Blood F Met 34, 1573-1584.
Urrutia, D.N., Caviedes, P., Mardones, R., Minguell, J.P.J., Vega-Letter, A.M., and Jofre, C.M. (2019). Comparative study of the neural differentiation capacity of mesenchymal stromal cells from different tissue sources: An approach for their use in neural regeneration therapies. Plos One 14.
Wang, J., Zhao, H.P., Fan, Z.B., Li, G.W., Ma, Q.F., Tao, Z., Wang, R.L., Feng, J., and Luo, Y.M. (2017). Long Noncoding RNA H19 Promotes Neuroinflammation in Ischemic Stroke by Driving Histone Deacetylase 1-Dependent M1 Microglial Polarization. Stroke 48, 2211-2221.
Wang, J.H., Liu, N., Du, H.W., Weng, J.S., Chen, R.H., Xiao, Y.C., and Zhang, Y.X. (2008). [Effects of adipose-derived stem cell transplantation on the angiogenesis and the expression of bFGF and VEGF in the brain post focal cerebral ischemia in rats]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24, 958-961.
Wang, Y.L., Guo, X.L., Liu, J., Zheng, Z.C., Liu, Y., Gao, W.Y., Xiao, J., Liu, Y.Q., Li, Y., Tang, M.L., et al. (2020). Olfactory ensheathing cells in chronic ischemic stroke: A phase 2, double-blind, randomized, controlled trial. J Neurorestoratology 8, 182-193.
Wu, C.X., Lin, J.L., Hong, M., Choudhury, Y., Balani, P., Leung, D., Dang, L.H., Zhao, Y., Zeng, J.M., and Wang, S. (2009). Combinatorial Control of Suicide Gene Expression by Tissue-specific Promoter and microRNA Regulation for Cancer Therapy. Mol Ther 17, 2058-2066.
Wu, Z.M., Zeng, M.Y., Li, C., Qiu, H.Y., Feng, H.X., Xu, X.N., Zhang, H.Y., and Wu, J. (2019). Time-dependence of NIHSS in predicting functional outcome of patients with acute ischemic stroke treated with intravenous thrombolysis. Postgrad Med J 95, 181-186.
Xie, J., Jones, T.J., Feng, D.N., Cook, T.G., Jester, A.A., Yi, R., Jawed, Y.T., Babbey, C., March, K.L., and Murphy, M.P. (2017). Human Adipose-Derived Stem Cells Suppress Elastase-Induced Murine Abdominal Aortic Inflammation and Aneurysm Expansion Through Paracrine Factors. Cell Transplant 26, 173-189.
Xu, J., Peng, H., Kang, N., Zhao, Z., Lin, J.H.C., Stanton, P.K., and Kang, J. (2007). Glutamate-induced exocytosis of glutamate from astrocytes. J Biol Chem 282, 24185-24197.
Xu, J.Y., and Sastry, B.R. (2005). Benzodiazepine involvement in LTP of the GABA-ergic IPSC in rat hippocampal CA1 neurons. Brain Res 1062, 134-143.
Yan, Y.F., Ma, T., Gong, K., Ao, Q., Zhang, X.F., and Gong, Y.D. (2014). Adipose-derived mesenchymal stem cell transplantation promotes adult neurogenesis in the brains of Alzheimer's disease mice. Neural Regen Res 9, 798-805.
Yeh, D.C., Chan, T.M., Harn, H.J., Chiou, T.W., Chen, H.S., Lin, Z.S., and Lin, S.Z. (2015). Adipose Tissue-Derived Stem Cells in Neural Regenerative Medicine. Cell Transplant 24, 487-492.
Zavan, B., Michelotto, L., Lancerotto, L., Della Puppa, A., D'Avella, D., Abatangelo, G., Vindigni, V., and Cortivo, R. (2010). Neural potential of a stem cell population in the adipose and cutaneous tissues. Neurol Res 32, 47-54.
Zhang, H.T., Liu, Z.L., Yao, X.Q., Yang, Z.J., and Xu, R.X. (2012). Neural differentiation ability of mesenchymal stromal cells from bone marrow and adipose tissue: a comparative study. Cytotherapy 14, 1203-1214.
Zhang, R., Zhong, C.K., Zhang, Y.H., Xie, X.W., Zhu, Z.B., Wang, A.L., Chen, C.S., Peng, Y.B., Peng, H., Li, Q.W., et al. (2019a). Immediate Antihypertensive Treatment for Patients With Acute Ischemic Stroke With or Without History of Hypertension A Secondary Analysis of the CATIS Randomized Clinical Trial. Jama Netw Open 2.
Zhang, Y., Deng, H., Hu, Y., Pan, C., Wu, G.F., Li, Q., and Tang, Z.P. (2019b). Adipose-derived mesenchymal stem cells stereotactic transplantation alleviate brain edema from intracerebral hemorrhage. J Cell Biochem 120, 14372-14382.
Zhang, Y., Tang, W.Y., Su, X.W., Dong, B.X., Wang, Q., Wang, Z.Y., Yang, Y.X., Qu, S.Q., and Luan, Z. (2018). Immunological effects of the intraparenchymal administration of allogeneic and autologous adipose-derived mesenchymal stem cells after the acute phase of middle cerebral artery occlusion in rats. J Transl Med 16.
Zhou, F., Gao, S.N., Wang, L., Sun, C.X., Chen, L., Yuan, P., Zhao, H.Y., Yi, Y., Qin, Y., Dong, Z.Q., et al. (2015). Human adipose-derived stem cells partially rescue the stroke syndromes by promoting spatial learning and memory in mouse middle cerebral artery occlusion model. Stem Cell Research & Therapy 6.
Zuk, P.A. (2010). The Adipose-derived Stem Cell: Looking Back and Looking Ahead. Mol Biol Cell 21, 1783-1787.