[1] Novikova N, De Boever P, Poddubko S, et al. Survey of environmental biocontamination on board the International Space Station[J]. Res Microbiol, 2006, 157(1): 5–12.
[2] Mccullough M J, Ross B C, Reade P C. Candida albicans: a review of its history, taxonomy, epidemiology, virulence attributes, and methods of strain differentiation[J]. Int J Oral Maxillofac Surg, 1996, 25(2): 136–44.
[3] Mayer F L, Wilson D, Hube B. Candida albicans pathogenicity mechanisms[J]. Virulence, 2013, 4(2): 119–28.
[4] Rosenzweig J A, Abogunde O, Thomas K, et al. Spaceflight and modeled microgravity effects on microbial growth and virulence[J]. Appl Microbiol Biotechnol, 2010, 85(4): 885–91.
[5] Sugita T, Yamazaki T, Makimura K, et al. Comprehensive analysis of the skin fungal microbiota of astronauts during a half-year stay at the International Space Station[J]. Med Mycol, 2016, 54(3): 232–9.
[6] Klaus D M, Howard H N. Antibiotic efficacy and microbial virulence during space flight[J]. Trends Biotechnol, 2006, 24(3): 131–6.
[7] Sonnenfeld G, Butel J S, Shearer W T. Effects of the space flight environment on the immune system[J]. Rev Environ Health, 2003, 18(1): 1–17.
[8] Crucian B, Stowe R P, Mehta S, et al. Alterations in adaptive immunity persist during long-duration spaceflight[J]. NPJ Microgravity, 2015, 1: 15013.
[9] Prasath K G, Sethupathy S, Pandian S K. Proteomic analysis uncovers the modulation of ergosterol, sphingolipid and oxidative stress pathway by myristic acid impeding biofilm and virulence in Candida albicans[J]. J Proteomics, 2019, 208: 103503.
[10] Li L, Liao Z, Yang Y, et al. Metabolomic profiling for the identification of potential biomarkers involved in a laboratory azole resistance in Candida albicans[J]. PLoS One, 2018, 13(2): e0192328.
[11] Avila M A, Garcia-Trevijano E R, Lu S C, et al. Methylthioadenosine[J]. Int J Biochem Cell Biol, 2004, 36(11): 2125–30.
[12] Pirkov I, Norbeck J, Gustafsson L, et al. A complete inventory of all enzymes in the eukaryotic methionine salvage pathway[J]. FEBS J, 2008, 275(16): 4111–20.
[13] Gow N a R, Yadav B. Microbe Profile: Candida albicans: a shape-changing, opportunistic pathogenic fungus of humans[J]. Microbiology, 2017, 163(8): 1145–1147.
[14] Erdogan A, Rao S S. Small intestinal fungal overgrowth[J]. Curr Gastroenterol Rep, 2015, 17(4): 16.
[15] Jiang W, Xu B, Yi Y, et al. Effects of simulated microgravity by RCCS on the biological features of Candida albicans[J]. Int J Clin Exp Pathol, 2014, 7(7): 3781–90.
[16] Altenburg S D, Nielsen-Preiss S M, Hyman L E. Increased filamentous growth of Candida albicans in simulated microgravity[J]. Genomics Proteomics Bioinformatics, 2008, 6(1): 42–50.
[17] Crabbe A, Nielsen-Preiss S M, Woolley C M, et al. Spaceflight enhances cell aggregation and random budding in Candida albicans[J]. PLoS One, 2013, 8(12): e80677.
[18] Hammond T G, Stodieck L, Birdsall H H, et al. Effects of microgravity on the virulence of Listeria monocytogenes, Enterococcus faecalis, Candida albicans, and methicillin-resistant Staphylococcus aureus[J]. Astrobiology, 2013, 13(11): 1081–90.
[19] Viaene J, Tiels P, Logghe M, et al. MET15 as a visual selection marker for Candida albicans[J]. Yeast, 2000, 16(13): 1205–15.
[20] Cooper A J, Bruschi S A, Iriarte A, et al. Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions[J]. Biochem J, 2002, 368(Pt 1): 253–61.
[21] Li D D, Wang Y, Dai B D, et al. ECM17-dependent methionine/cysteine biosynthesis contributes to biofilm formation in Candida albicans[J]. Fungal Genet Biol, 2013, 51: 50–9.
[22] Garcia-Sanchez S, Aubert S, Iraqui I, et al. Candida albicans biofilms: a developmental state associated with specific and stable gene expression patterns[J]. Eukaryot Cell, 2004, 3(2): 536–45.
[23] Li J, Zhang B, Ma T, et al. Role of the Inositol Polyphosphate Multikinase Ipk2 in Regulation of Hyphal Development, Calcium Signaling and Secretion in Candida albicans[J]. Mycopathologia, 2017, 182(7–8): 609–623.
[24] Fiorini A, Rosado F R, Bettega E M, et al. Candida albicans PROTEIN PROFILE CHANGES IN RESPONSE TO THE BUTANOLIC EXTRACT OF Sapindus saponariaL[J]. Rev Inst Med Trop Sao Paulo, 2016, 58: 25.
[25] Wisniewski J R, Zougman A, Nagaraj N, et al. Universal sample preparation method for proteome analysis[J]. Nat Methods, 2009, 6(5): 359–62.
[26] Elias J E, Gygi S P. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry[J]. Nat Methods, 2007, 4(3): 207–14.
[27] Tyanova S, Temu T, Sinitcyn P, et al. The Perseus computational platform for comprehensive analysis of (prote)omics data[J]. Nat Methods, 2016, 13(9): 731–40.