Research Articleposted 2024-11-08 10:50:50
Quantifying natural amyloid plaque accumulation in the continuum of Alzheimer’s disease using ADNI
Marwa E. Elhefnawy, Noel Patson, Samer Mouksassi, Goonaseelan (Colin) Pillai, Sergey Shcherbinin, Emmanuel Chigutsa, Ivelina Gueorguieva
Under Review
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Research Articleposted 2024-08-28 20:00:24
Model informed approach to estimate treatment effect in placebo- controlled clinical trials using an artificial intelligence based propensity weighting methodology to account for non-specific responses to treatment
Roberto Gomeni, Francoise Bressolle-Gomeni
Under Review
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Research Articleposted 2024-08-14 07:57:48
Reliability of in vitro data for the mechanistic prediction of brain extracellular fluid pharmacokinetics of P-glycoprotein substrates in vivo; are we scaling correctly?
Daan Willem van Valkengoed, Makoto Hirasawa, Vivi Rottschäfer, Elizabeth Cunera Maria de Lange
Under Revision
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Research Articleposted 2024-08-06 11:27:02
Whole-Body Physiologically-Based Pharmacokinetic Modeling of GalNAc conjugated siRNAs
Emilie Kirstine Langeskov Salim, Erik Sjögren, Kim Kristensen
Under Review
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Research Articleposted 2024-07-18 20:14:17
Application of Model-informed Drug Development (MIDD) in Regulatory Submissions for Drug Approval in Japan
Tomohiro Sasaki, Takayuki Katsube, Seiichi Hayato, Shingo Yamaguchi, Jun Tanaka, Hiroki Yoshimatsu, Yushi Nakanishi, and 5 more authors
Under Review
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Research Articleupdated 2024-04-22 19:55:29
Note On Importance of Correct Stoichiometric Assumptions for Modeling of Monoclonal Antibodies
Leonid Gibiansky, Ekaterina Gibiansky
Under Review
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Research Articleposted 2024-04-03 07:12:51
Evaluation of ChatGPT and Gemini Large Language Models for Pharmacometrics with NONMEM
Euibeom Shin, Yifan Yu, Robert R. Bies, Murali Ramanathan
Published
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Research Articleposted 2024-02-27 08:39:16
Stochastic pharmacodynamics of a heterogeneous tumour-cell population
Van Thuy Truong, Paolo Vicini, James Yates, Vincent Dubois, Grant Lythe
Under Revision
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Research Articleposted 2024-02-26 15:52:02
A hybrid PKPD agent-based model of the tumour immune interaction: effects of anti-cancer combination therapy
Van Thuy Truong, James Yates, Paolo Vicini, Vincent Dubois, Grant Lythe
Under Review
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Research Articleposted 2024-02-01 05:18:19
Target-Mediated Drug Disposition Model for Drugs with N>2 Binding Sites That Bind to a Target with One Binding Site
Leonid Gibiansky, Chee M Ng, Ekaterina Gibiansky
Published
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