Mitochondrial RNA cytosolic leakage drives the SASP
A plasma proteomic signature links secretome of senescent monocytes to aging- and obesity-related clinical outcomes in humans
Impaired ketogenesis in Leydig Cells drives testicular aging
Loss of myosin light chain kinase induces the cellular senescence-associated secretory phenotype to promote breast epithelial cell migration
Derivation of human primary prostate epithelial cell lines by differentially targeting the CDKN2A locus along with expression of hTERT
Spatial analysis of the bone microenvironment reveals a novel osteoblast-CD4+ CTL crosstalk mediated by the SIRT1/DAAM2 axis
Limited Cell-Autonomous Anticancer Mechanisms in Long-Lived Bats
Auto-sumoylation of the Ubc9 E2 SUMO-conjugating Enzyme Extends Cellular Lifespan
TRIM37 maintains 5hmC levels and stemness through preventing DNMT1 alternative splicing
Single-cell Transcriptome Analysis Identifies Senescent Osteocytes as Contributors to Bone Destruction in Breast Cancer Metastasis