Articleposted 2024-11-05 07:01:36
Autophagy-lysosomal dysfunction, intraneuronal amyloidosis, and selective neuron death yield senile plaques in preclinical late-onset Alzheimer’s Disease
Ralph Nixon, Ju-Hyun Lee, Philip Stavrides, Sandipkumar Darji, Chris Goulbourne, Martin Berg, Panaiyur Mohan, and 9 more authors
Under Review
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Articleposted 2024-11-04 16:09:57
Microglia modulate Aβ-dependent astrocyte reactivity in Alzheimer’s disease
Eduardo Zimmer, João Pedro Ferrari-Souza, Guilherme Povala, Nesrine Rahmouni, Bruna Bellaver, Pamela Ferreira, Douglas Leffa, and 24 more authors
Under Review
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Resourceposted 2024-10-28 03:01:18
Human-mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome
Junmin Peng, Jay Yarbro, Xian Han, Abhijit Dasgupta, Ka Yang, Danting Liu, Him Shrestha, and 24 more authors
Under Review
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Biological Sciences - Articleposted 2024-10-02 15:19:43
Noradrenergic axon loss drives olfactory dysfunction in Alzheimer’s disease
Carolin Meyer, Theresa Niedermeier, Paul Feyen, Felix Strübing, Boris Rauchmann, Johanna Gentz, Yannik Tillmann, and 17 more authors
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Articleposted 2024-09-30 11:39:55
Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in male 3xTg Alzheimer’s model mice
John Gigg, Grace Cunliffe, Li Yang Tan, Sangyong Jung, Jonathan Turner
Under Review
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Articleposted 2024-08-28 02:49:58
Transcriptomic, cellular, and functional signatures of white matter damage in Alzheimer’s disease
Bharat Biswal, Yilu Li, Pan Wang, Jinzhong Peng, Lin Liu, Fanyu Zhang, Yasser Iturria-Medina, and 1 more authors
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Articleposted 2024-08-09 13:55:58
Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions.
Joseph Giorgio, Caroline Jonson, Yilin Wang, Jennifer Yokoyama, Jingshen Wang, William Jagust
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Articleposted 2024-07-02 02:52:53
APOE4 and sedentary lifestyle synergistically impair neurovascular function in the visual cortex of awake mice
Catherine Hall, Silvia Anderle, Orla Bonnar, Joseph Henderson, Kira Shaw, Andre Chagas, Letitia McMullan, and 3 more authors
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Biological Sciences - Articleposted 2024-05-30 10:53:53
A roadmap to human hippocampal neurogenesis in adulthood, aging and AD.
Orly Lazarov, Ahmed Disouky, Mark Sanborn, Mostafa Mostafa, K. Sabitha, Aimee Schantz, Namhee Kim, and 7 more authors
Posted
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Biological Sciences - Articleposted 2024-05-24 05:01:19
Alzheimer’s disease risk allele of PICALM causes detrimental lipid droplets in microglia
Jubao Duan, Alena Kozlova, Siwei Zhang, Ari Sudwards, Hanwen Zhang, Stanislau Smirnou, Xiaotong Sun, and 9 more authors
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